{"id":"W2468396337","doi":"10.1021/acs.jproteome.6b00199","title":"Automated SDS Depletion for Mass Spectrometry of Intact Membrane Proteins though Transmembrane Electrophoresis","year":2016,"lang":"en","type":"article","venue":"Journal of Proteome Research","topic":"Advanced Proteomics Techniques and Applications","field":"Chemistry","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Proteome; Chromatography; Membrane protein; Chemistry; Sodium dodecyl sulfate; Transmembrane protein; Lysis; Mass spectrometry; Gel electrophoresis; Two-dimensional gel electrophoresis; Tandem mass spectrometry; Membrane; Proteomics; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006964391,0.0008164934,0.0005773241,0.000728498,0.0003946653,0.0006761927,0.0005966378,0.0006339998,0.001286669],"category_scores_gemma":[0.000650824,0.0002868464,0.0003550359,0.0005266618,0.0003201581,0.0005622298,0.0007709181,0.000836749,0.001384482],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002723752,"about_ca_system_score_gemma":0.0004573634,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002599204,"about_ca_topic_score_gemma":0.0004911202,"domain_scores_codex":[0.9992892,0.0001273998,0.00004960629,0.0001804574,0.000302773,0.00005054293],"domain_scores_gemma":[0.9996339,0.0001251654,0.00006655262,0.00007506794,0.00007455297,0.00002470966],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000279142,0.00001501947,0.0001193373,0.00006780619,0.000009636684,0.00002629644,0.00002034785,0.00004387284,0.9945855,0.0001514108,0.0002098255,0.004723194],"study_design_scores_gemma":[0.000008550068,0.0000731773,0.001471029,0.00001366016,0.000009703458,0.0001964364,0.0000191257,0.00211305,0.9871738,0.0002138741,0.008695301,0.0000122787],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.394211,0.005634009,0.5861182,0.0006777683,0.0003088776,0.0005153426,0.004030152,0.004120269,0.004384333],"genre_scores_gemma":[0.4061793,0.007106262,0.5684701,0.0005601434,0.0001626827,0.001220442,0.007611922,0.000753801,0.007935206],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.001286669,"threshold_uncertainty_score":0.00430429,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03591061143765507,"score_gpt":0.3650657491616904,"score_spread":0.3291551377240354,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}