{"id":"W2468937966","doi":"10.1109/embsisc.2016.7508598","title":"Predicting novel protein-protein interactions between the HIV-1 virus and homo sapiens","year":2016,"lang":"en","type":"article","venue":"","topic":"Machine Learning in Bioinformatics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University","funders":"","keywords":"Human immunodeficiency virus (HIV); Protein–protein interaction; Computer science; Virus; Computational biology; Homo sapiens; Biology; Virology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001941707,0.0001205302,0.00008393495,0.0000239407,0.0001627673,0.00003770096,0.0001651616,0.00007208884,0.00005932863],"category_scores_gemma":[0.000280048,0.00006395496,0.00004011731,0.0000428809,0.0001004468,0.00000823982,0.000210958,0.000122782,0.00004574214],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009449512,"about_ca_system_score_gemma":0.00002240553,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003580358,"about_ca_topic_score_gemma":0.00004008547,"domain_scores_codex":[0.9993139,0.00003101546,0.0002006774,0.0001697118,0.00009541836,0.0001892852],"domain_scores_gemma":[0.9994553,0.00003379164,0.00009774781,0.0003099217,0.00004451796,0.00005872234],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001409249,0.00001761838,0.02269415,0.00001496039,0.00005262972,2.049628e-7,0.00008320226,0.000003381066,0.9677991,0.0002902366,0.0005774882,0.008452878],"study_design_scores_gemma":[0.001497039,0.0004448499,0.03724066,0.0001754082,0.00005212211,0.00006122939,0.0002207905,0.0008771116,0.7114221,0.0002061371,0.2472461,0.0005564248],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9338431,0.00002692663,0.05832688,0.001781465,0.00004155019,0.0003414477,0.00006692541,0.00003502955,0.005536691],"genre_scores_gemma":[0.9882771,0.000006223629,0.004539062,0.0001279183,0.0002663377,0.00004070138,0.00002423504,0.00001590039,0.006702563],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2563771,"threshold_uncertainty_score":0.2608007,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01009606207177598,"score_gpt":0.2510060298348622,"score_spread":0.2409099677630862,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}