{"id":"W2469109222","doi":"10.1016/s1470-2045(16)30097-3","title":"Obinutuzumab plus bendamustine versus bendamustine monotherapy in patients with rituximab-refractory indolent non-Hodgkin lymphoma (GADOLIN): a randomised, controlled, open-label, multicentre, phase 3 trial","year":2016,"lang":"en","type":"article","venue":"The Lancet Oncology","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":343,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta; University of British Columbia; BC Cancer Agency","funders":"Genentech; F. Hoffmann-La Roche; Gilead Sciences","keywords":"Bendamustine; Obinutuzumab; Medicine; Rituximab; Internal medicine; Neutropenia; Population; Oncology; Surgery; Lymphoma; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001473626,0.002002107,0.00304278,0.0003920235,0.0004257184,0.001404446,0.0009566858,0.001654345,0.00439697],"category_scores_gemma":[0.001563987,0.000730012,0.001945126,0.0004718283,0.001446325,0.001485061,0.0005351857,0.003281187,0.0008719712],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00108502,"about_ca_system_score_gemma":0.0009124015,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001189038,"about_ca_topic_score_gemma":0.002640948,"domain_scores_codex":[0.9994585,0.0002670453,0.0000270791,0.00009796653,0.00003153477,0.0001178344],"domain_scores_gemma":[0.9992288,0.0002111425,0.0001635424,0.00005398233,0.0000358311,0.00030659],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9847696,0.002719268,0.000405967,0.0004005253,0.0006997861,0.00003160687,0.00006227873,0.0002901805,0.001676845,0.00008291617,0.0003700308,0.008491029],"study_design_scores_gemma":[0.9582516,0.03934701,0.001036113,0.00003010557,0.0003116592,0.00002908383,0.00002820502,0.0002170321,0.0001950317,0.0001728658,0.0003689174,0.000012411],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895669,0.00526758,0.0004391768,0.0007176099,0.0005830528,0.001429342,0.0005370013,0.00006769078,0.001391626],"genre_scores_gemma":[0.9910907,0.002613374,0.0008796647,0.000841644,0.0003160876,0.001292568,0.0006971202,0.00002109582,0.002247837],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00439697,"threshold_uncertainty_score":0.01470935,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05570320220474047,"score_gpt":0.3646952439096892,"score_spread":0.3089920417049487,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}