{"id":"W2469454278","doi":"10.1016/j.stem.2016.06.004","title":"The Central Nervous System Regulates Embryonic HSPC Production via Stress-Responsive Glucocorticoid Receptor Signaling","year":2016,"lang":"en","type":"article","venue":"Cell stem cell","topic":"Zebrafish Biomedical Research Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; Beth Israel Deaconess Medical Center","keywords":"Biology; Glucocorticoid receptor; Progenitor cell; Embryonic stem cell; Haematopoiesis; Endocrinology; Cell biology; Internal medicine; Glucocorticoid; Progenitor; Central nervous system; Stem cell; Medicine; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001170847,0.0003846195,0.0002311985,0.0003453235,0.0002867373,0.0004619567,0.000184665,0.0002311139,0.001135283],"category_scores_gemma":[0.0001474544,0.0001763045,0.0002427808,0.0001545192,0.0004525306,0.000295057,0.0004025612,0.0006614027,0.0002573021],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009372392,"about_ca_system_score_gemma":0.0004441991,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002934023,"about_ca_topic_score_gemma":0.008860343,"domain_scores_codex":[0.9998419,0.00001903088,0.00001083849,0.00004271678,0.00003482886,0.00005060886],"domain_scores_gemma":[0.9997901,0.00001360779,0.00006714993,0.0000157104,0.0000449013,0.00006850825],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007193154,0.000004606761,0.0004790109,0.00002458135,0.000005682962,0.0001110569,0.00001895475,0.00003472357,0.9970359,0.0002912444,0.0001316164,0.001790705],"study_design_scores_gemma":[0.00002626941,0.0001182777,0.06795993,0.00003066917,0.00004971788,0.0003456737,0.0002592781,0.0006667516,0.9247019,0.0002714989,0.005550711,0.0000192988],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9767784,0.008477826,0.006646727,0.0006053129,0.0001207573,0.00004071114,0.001134374,0.0002159259,0.005980035],"genre_scores_gemma":[0.9904756,0.002007709,0.002142397,0.0001200979,0.00001942239,0.00002877707,0.0003500188,0.00005319546,0.004802864],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002934023,"threshold_uncertainty_score":0.006800175,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006067117566223565,"score_gpt":0.2174242911644713,"score_spread":0.2113571735982477,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}