{"id":"W2469624798","doi":"10.1038/cddis.2016.175","title":"NUPR1, a new target in liver cancer: implication in controlling cell growth, migration, invasion and sorafenib resistance","year":2016,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":142,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Hôtel-Dieu de Québec; Centre hospitalier universitaire de Québec","funders":"Ministero dell’Istruzione, dell’Università e della Ricerca","keywords":"Sorafenib; Gene knockdown; Gene silencing; Cancer research; Cell growth; RELB; Viability assay; Biology; Cell migration; Cell; Apoptosis; Transcription factor; Hepatocellular carcinoma; Gene; NFKB1","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001779459,0.0003889264,0.0004235233,0.0003152322,0.000227588,0.0003880739,0.0002227402,0.0003103142,0.0008246396],"category_scores_gemma":[0.0001547831,0.0001284813,0.0002731656,0.0002982213,0.0002374133,0.0004519047,0.0002594458,0.0005247329,0.0002687433],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002732172,"about_ca_system_score_gemma":0.0002412004,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002733743,"about_ca_topic_score_gemma":0.0004066498,"domain_scores_codex":[0.999884,0.00001422124,0.000007863788,0.00004023535,0.0000360058,0.00001761108],"domain_scores_gemma":[0.9999218,0.00001172471,0.00003263591,0.000005901948,0.0000114041,0.00001643776],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002628883,0.00003031705,0.001561517,0.000534595,0.00002059915,0.0003606722,0.00007297757,0.000430331,0.9732893,0.0006443701,0.0004382138,0.02235425],"study_design_scores_gemma":[0.00008509748,0.00107916,0.04727266,0.00009088762,0.0001817845,0.006583467,0.0002574328,0.007066512,0.868052,0.00165579,0.06761123,0.00006402883],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8303429,0.1358555,0.0251327,0.001394757,0.0002083196,0.00009562993,0.001433115,0.0007564132,0.00478067],"genre_scores_gemma":[0.9603984,0.02675845,0.007618512,0.0002283373,0.00007438019,0.00007931772,0.001324133,0.00005216498,0.003466105],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008246396,"threshold_uncertainty_score":0.002758682,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01456404389933745,"score_gpt":0.2428291333935975,"score_spread":0.2282650894942601,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}