{"id":"W2469624798","doi":"10.1038/cddis.2016.175","title":"NUPR1, a new target in liver cancer: implication in controlling cell growth, migration, invasion and sorafenib resistance","year":2016,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":142,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Hôtel-Dieu de Québec; Centre hospitalier universitaire de Québec","funders":"Ministero dell’Istruzione, dell’Università e della Ricerca","keywords":"Sorafenib; Gene knockdown; Gene silencing; Cancer research; Cell growth; RELB; Viability assay; Biology; Cell migration; Cell; Apoptosis; Transcription factor; Hepatocellular carcinoma; Gene; NFKB1","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000604437,0.0000978083,0.0001428981,0.0001009534,0.00004130818,0.00001735553,0.00002476848,0.00003679587,0.00006155585],"category_scores_gemma":[0.00008859798,0.00007201615,0.00002865156,0.00008672161,0.00002117793,0.0001249911,0.00001257341,0.00006144133,0.000005220794],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000534433,"about_ca_system_score_gemma":0.0001814637,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004716828,"about_ca_topic_score_gemma":0.0004323657,"domain_scores_codex":[0.9993348,0.00002134238,0.0001863138,0.0002428517,0.00007393875,0.0001407645],"domain_scores_gemma":[0.999392,0.00006465802,0.00005474468,0.0001102947,0.00004940006,0.0003289512],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002478324,0.0003971192,0.5812013,0.0004150265,0.000008065412,0.00009603381,0.0007535262,0.0000174928,0.4043567,0.000703339,0.006839835,0.002733246],"study_design_scores_gemma":[0.02385302,0.0002842131,0.8267669,0.002183544,0.0002525599,0.000008616084,0.0002442452,0.003633071,0.1064167,0.008878256,0.0267458,0.0007330708],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9868806,0.008745751,0.0007156172,0.002655997,0.00003577202,0.0003129023,0.00003229487,0.00001689915,0.0006041835],"genre_scores_gemma":[0.9950901,0.003006824,0.0002404532,0.0003355637,0.00008568347,0.00003884434,0.00001781092,0.000009782569,0.001174999],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.29794,"threshold_uncertainty_score":0.2936733,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01456404389933745,"score_gpt":0.2428291333935975,"score_spread":0.2282650894942601,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}