{"id":"W2469826629","doi":"10.1093/infdis/jiw294","title":"The Bacterial Stress-Responsive Hsp90 Chaperone (HtpG) Is Required for the Production of the Genotoxin Colibactin and the Siderophore Yersiniabactin in<i>Escherichia coli</i>","year":2016,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique; Armand Frappier Museum","funders":"Medical Research Council; Natural Sciences and Engineering Research Council of Canada; Agence Nationale de la Recherche; Institut National Du Cancer; Equipex","keywords":"Virulence; Biology; Nonribosomal peptide; Siderophore; Escherichia coli; Chaperone (clinical); Heat shock protein; Pathogenicity island; Microbiology; Gene; Genetics; Biosynthesis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001254768,0.0001737521,0.000232208,0.00002632431,0.0006186322,0.00005068769,0.0004618653,0.00006086805,0.000007726008],"category_scores_gemma":[0.004512081,0.00005605822,0.0001901524,0.0001748914,0.001223013,0.0000185606,0.000239498,0.0001800605,5.147973e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000451336,"about_ca_system_score_gemma":0.0003026181,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004877333,"about_ca_topic_score_gemma":0.0002687484,"domain_scores_codex":[0.9980769,0.000808203,0.0003910262,0.0001558419,0.000295088,0.0002729501],"domain_scores_gemma":[0.9968523,0.001664992,0.0005432462,0.0004579556,0.0004268366,0.00005464389],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0114631,0.0001612555,0.005883434,0.00003675917,0.0006011378,9.070527e-7,0.001250702,0.00004453299,0.9735534,0.00007148962,0.004742799,0.002190543],"study_design_scores_gemma":[0.01404832,0.003050372,0.2443057,0.0005487752,0.001267501,0.0001691124,0.008107659,0.00007257323,0.6799641,0.002166915,0.04570047,0.000598473],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9815838,0.004346113,0.0000315472,0.01243912,0.0005150967,0.0009955632,0.00005180821,0.000003524759,0.00003345367],"genre_scores_gemma":[0.9915595,0.007235729,0.000006694395,0.0002687712,0.0005827809,0.00007787485,6.022445e-7,0.00002061774,0.0002473956],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2935892,"threshold_uncertainty_score":0.5401708,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008675950234390077,"score_gpt":0.2513514380686924,"score_spread":0.2426754878343023,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}