{"id":"W2469936520","doi":"10.1007/s12013-014-0362-1","title":"Cytoskeletal Alterations and Biomechanical Properties of parkin-Mutant Human Primary Fibroblasts","year":2014,"lang":"en","type":"article","venue":"Cell Biochemistry and Biophysics","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Cytoskeleton; Cell biology; Mutant; Parkin; Biology; Genetics; Medicine; Pathology; Cell; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001509911,0.0001848559,0.0001676305,0.0002337138,0.0003450894,0.0001981821,0.0001518641,0.0002484837,0.001977709],"category_scores_gemma":[0.0001737877,0.0002009068,0.0002444646,0.0002415463,0.0001640546,0.0002371466,0.0001590764,0.0003377736,0.0003897556],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001635898,"about_ca_system_score_gemma":0.000157563,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0029177,"about_ca_topic_score_gemma":0.002289434,"domain_scores_codex":[0.9998472,0.00001914804,0.00002357442,0.00003204676,0.00004609529,0.0000318839],"domain_scores_gemma":[0.9998443,0.00004423034,0.00002339737,0.00002838554,0.0000286488,0.00003113139],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000133695,0.00003115936,0.0006805834,0.00001700402,0.000005389812,0.0002017805,0.00006953035,0.00005829958,0.9980341,0.00008474728,0.00002816797,0.0006554773],"study_design_scores_gemma":[0.00003149159,0.0005355902,0.0779513,0.000009278885,0.00004489358,0.001685137,0.0004013137,0.001464084,0.9153227,0.0001494724,0.002391149,0.00001350454],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965804,0.0004829117,0.0008380623,0.00003831343,0.00001530347,0.00001046816,0.0004626167,0.000016574,0.001555297],"genre_scores_gemma":[0.9961482,0.0003967048,0.0004542192,0.00003010786,0.000005225264,0.00002374405,0.0006143068,0.000006988976,0.002320454],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0029177,"threshold_uncertainty_score":0.006616116,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01008289316411202,"score_gpt":0.2161275992626903,"score_spread":0.2060447060985783,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}