{"id":"W2470303798","doi":"10.2119/molmed.2015.00017","title":"Mouse Model for Protein Tyrosine Phosphatase D (PTPRD) Associations with Restless Leg Syndrome or Willis-Ekbom Disease and Addiction: Reduced Expression Alters Locomotion, Sleep Behaviors and Cocaine-Conditioned Place Preference","year":2015,"lang":"en","type":"article","venue":"Molecular Medicine","topic":"Restless Legs Syndrome Research","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute on Drug Abuse; National Institutes of Health; U.S. Department of Health and Human Services","keywords":"Addiction; Phenotype; Biology; Protein tyrosine phosphatase; Gene; Disease; Genetics; Neuroscience; Medicine; Internal medicine; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004301151,0.001544347,0.0005693831,0.002050456,0.0005393933,0.0005058663,0.0007060082,0.001687837,0.00996769],"category_scores_gemma":[0.0003038751,0.0005789367,0.0007744605,0.0006652698,0.000768044,0.000387825,0.0006259776,0.001479919,0.001405356],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005029049,"about_ca_system_score_gemma":0.0003409203,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007671608,"about_ca_topic_score_gemma":0.001871401,"domain_scores_codex":[0.9994004,0.00009897219,0.0000938478,0.0002090694,0.0001096671,0.00008799831],"domain_scores_gemma":[0.9994804,0.00008893292,0.0002053906,0.00004872741,0.00002575968,0.0001507468],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001565351,0.0009140019,0.004137195,0.0001418059,0.0001170455,0.002337433,0.0001743559,0.0001866003,0.9847251,0.0009522011,0.0005745616,0.004174446],"study_design_scores_gemma":[0.003546116,0.009486127,0.1580737,0.0003308947,0.001088076,0.04473178,0.0008769865,0.009128763,0.7294579,0.002080994,0.04103887,0.0001597245],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887033,0.0006650394,0.005010883,0.0003970058,0.0001123868,0.0001894115,0.003045471,0.0003095828,0.001566807],"genre_scores_gemma":[0.9575512,0.001040031,0.01400159,0.0004067013,0.00007058451,0.0007128389,0.006218666,0.0002579649,0.01974043],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00996769,"threshold_uncertainty_score":0.03334522,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0543771040834541,"score_gpt":0.3145725541751821,"score_spread":0.260195450091728,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}