{"id":"W2470398165","doi":"10.1016/j.mod.2016.06.005","title":"Steroid 5-reductases are functional during early frog development and are regulated via DNA methylation","year":2016,"lang":"en","type":"article","venue":"Mechanisms of Development","topic":"Hormonal and reproductive studies","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Royal Military College of Canada","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; DNA methylation; Vertebrate; Epigenetics; Gene; Imprinting (psychology); Methylation; Regulation of gene expression; Amphibian; Mechanism (biology); Gene expression; Genetics; Cell biology; Ecology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002417821,0.0002140767,0.0003866077,0.0001644851,0.0001950127,0.000006950924,0.00004594756,0.00007028104,0.00006404676],"category_scores_gemma":[0.00006560413,0.0001363938,0.00004065101,0.0001232758,0.00006429798,0.00009277448,0.0001183666,0.00006226863,0.00002554338],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001474879,"about_ca_system_score_gemma":0.0001099901,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003106901,"about_ca_topic_score_gemma":0.000008675895,"domain_scores_codex":[0.9984165,0.00002741248,0.0004395209,0.0004275174,0.0004567222,0.0002323653],"domain_scores_gemma":[0.9991918,0.00002790056,0.0002373155,0.0001530607,0.0002840906,0.0001058233],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000411354,0.0001500799,0.01005001,0.000166867,0.0004758085,0.00001960974,0.001258495,7.395113e-7,0.9547927,0.0001482519,0.00003711337,0.03248901],"study_design_scores_gemma":[0.0006943273,0.00004307344,0.4958825,0.000210866,0.0000183972,0.00001300563,0.0002824762,2.588057e-7,0.502076,0.0004202749,0.0002474476,0.0001113962],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991004,0.0003993211,0.007251468,0.0007392717,0.0001781243,0.0003024764,0.000005221495,0.00006165005,0.00005847963],"genre_scores_gemma":[0.9825718,0.00002282444,0.01530434,0.0000239651,0.00006546456,0.00004758975,0.00001167534,0.00002016833,0.001932201],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4858325,"threshold_uncertainty_score":0.5561979,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02086944223522124,"score_gpt":0.218100427626194,"score_spread":0.1972309853909727,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}