{"id":"W2471073614","doi":"10.1182/blood.v126.23.731.731","title":"Efficacy and Safety of Carfilzomib, Lenalidomide, and Dexamethasone Vs Lenalidomide and Dexamethasone in Patients with Relapsed Multiple Myeloma Based on Cytogenetic Risk Status: Subgroup Analysis from the Phase 3 Study Aspire (NCT01080391)","year":2015,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Lenalidomide; Carfilzomib; Dexamethasone; Multiple myeloma; Medicine; Oncology; Pomalidomide; Internal medicine; Subgroup analysis; Thalidomide; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0027995,0.0009932427,0.003269982,0.0006538648,0.0003430815,0.001075486,0.000705768,0.0009769384,0.002797022],"category_scores_gemma":[0.002313012,0.0003915258,0.007379195,0.0006589448,0.0004481002,0.0006066996,0.0006255073,0.001596427,0.0003667378],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000869251,"about_ca_system_score_gemma":0.001028336,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008244598,"about_ca_topic_score_gemma":0.003219937,"domain_scores_codex":[0.9986116,0.0006016249,0.0002372927,0.0002115371,0.0001577347,0.0001802651],"domain_scores_gemma":[0.9987866,0.0004210935,0.0002858013,0.0001908436,0.00007725372,0.0002384344],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.9092163,0.002008042,0.02805348,0.0009355009,0.02285972,0.0001716939,0.0001591233,0.0009879369,0.005588086,0.0001303754,0.001527647,0.02836209],"study_design_scores_gemma":[0.6012263,0.1693711,0.1658455,0.0003095111,0.04832029,0.0006977821,0.0003654714,0.003703938,0.003362056,0.001560592,0.005082931,0.0001545123],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9885167,0.007031928,0.0003090318,0.0004208896,0.0001353457,0.0008444299,0.001783133,0.00002675313,0.0009317936],"genre_scores_gemma":[0.9957622,0.0008363992,0.0003312411,0.0004216146,0.0001185322,0.0006990507,0.001419869,0.000007972133,0.0004031709],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003269982,"threshold_uncertainty_score":0.01480532,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02159025863719672,"score_gpt":0.2805427240642102,"score_spread":0.2589524654270135,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}