{"id":"W2471234061","doi":"10.1038/srep28846","title":"Differential induction of muscle atrophy pathways in two mouse models of spinal muscular atrophy","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Neurogenetic and Muscular Disorders Research","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"E-Rare; Canadian Institutes of Health Research; University of Ottawa; Cure SMA; Muscular Dystrophy Association","keywords":"Spinal muscular atrophy; Atrophy; Muscle atrophy; Medicine; Neuroscience; Pathology; Anatomy; Biology; Physical medicine and rehabilitation; Bioinformatics; Disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004750681,0.0001334464,0.0003410717,0.0004123586,0.00005307413,0.0000154666,0.0001025372,0.00005782156,0.0001460997],"category_scores_gemma":[0.0001027203,0.00009265925,0.0002354923,0.0004733964,0.000441505,0.000110609,0.00009748029,0.0001095168,0.000004758684],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004331821,"about_ca_system_score_gemma":0.0002321872,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001152464,"about_ca_topic_score_gemma":0.00001880919,"domain_scores_codex":[0.9974567,0.00007300267,0.0006330482,0.0005917799,0.0009339889,0.0003114845],"domain_scores_gemma":[0.9984472,0.00001046989,0.0002391447,0.0008940065,0.0002748156,0.0001343235],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009733524,0.000311547,0.003458765,0.0001050767,0.00002378336,0.0001712177,0.0001151204,0.00005910621,0.9756026,0.0001452665,0.00008683197,0.01982332],"study_design_scores_gemma":[0.003030701,0.0005876934,0.0292656,0.0003542137,0.00008679571,0.0001756662,0.0001524238,0.0004947562,0.9553307,0.009364504,0.0009103611,0.000246634],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953038,0.0001806909,0.002769998,0.0000708619,0.0008455094,0.0005040682,0.000003907576,0.00001723283,0.0003040003],"genre_scores_gemma":[0.9990453,0.00003633024,0.0003129326,0.000004127489,0.00004551095,0.00001923539,0.00001083626,0.00002048519,0.0005052479],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02580684,"threshold_uncertainty_score":0.3778535,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03426011041092409,"score_gpt":0.2920538799352685,"score_spread":0.2577937695243444,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}