{"id":"W2471234061","doi":"10.1038/srep28846","title":"Differential induction of muscle atrophy pathways in two mouse models of spinal muscular atrophy","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Neurogenetic and Muscular Disorders Research","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"E-Rare; Canadian Institutes of Health Research; University of Ottawa; Cure SMA; Muscular Dystrophy Association","keywords":"Spinal muscular atrophy; Atrophy; Muscle atrophy; Medicine; Neuroscience; Pathology; Anatomy; Biology; Physical medicine and rehabilitation; Bioinformatics; Disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005493218,0.001375557,0.0006697908,0.002691462,0.0004487021,0.0005300071,0.0004868922,0.001037131,0.002287248],"category_scores_gemma":[0.0002092086,0.0005680518,0.00090949,0.0006324168,0.0007769669,0.0006089978,0.0007224318,0.001848812,0.000580535],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006155557,"about_ca_system_score_gemma":0.000507005,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006260701,"about_ca_topic_score_gemma":0.001957025,"domain_scores_codex":[0.9990578,0.0001578493,0.000172822,0.000263643,0.0002012624,0.0001466176],"domain_scores_gemma":[0.9993683,0.00005421513,0.0002342716,0.00005811428,0.00004355668,0.0002416551],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004107328,0.0001365242,0.0003153343,0.00004612108,0.00001512144,0.00007327257,0.00002844072,0.00002386545,0.9981165,0.0001278423,0.00004271087,0.0006636474],"study_design_scores_gemma":[0.0002024628,0.003166806,0.01482514,0.00005195451,0.0001160615,0.001260865,0.0001406308,0.0007511916,0.9761579,0.0002221677,0.003073817,0.00003104654],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9862493,0.001994699,0.006873216,0.0003533558,0.0001365883,0.0002376263,0.002052029,0.0003342873,0.001768811],"genre_scores_gemma":[0.9542298,0.003772106,0.02336062,0.0003592834,0.00005496464,0.001320343,0.004918506,0.0002443974,0.01174001],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002691462,"threshold_uncertainty_score":0.007651567,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03426011041092409,"score_gpt":0.2920538799352685,"score_spread":0.2577937695243444,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}