{"id":"W2471236952","doi":"10.1128/aac.02365-17","title":"Chemogenomic Profiling of the Fungal Pathogen Candida albicans","year":2017,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"Canadian Institutes of Health Research","keywords":"Anidulafungin; Caspofungin; Candida albicans; Biology; Echinocandins; Antifungal drug; Fluconazole; Microbiology; Drug resistance; Corpus albicans; Posaconazole; Drug; Gene; Computational biology; Voriconazole; Genetics; Pharmacology; Antifungal","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001186708,0.0002994715,0.0003528385,0.001229508,0.000299332,0.0004825242,0.0001767834,0.0003157101,0.0006885697],"category_scores_gemma":[0.0003775307,0.00009512702,0.0002909747,0.001359789,0.0001413355,0.0001769433,0.0003214605,0.0003695942,0.0003208512],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001848783,"about_ca_system_score_gemma":0.0001842133,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009964957,"about_ca_topic_score_gemma":0.001076873,"domain_scores_codex":[0.9997147,0.00002390457,0.00001640916,0.000076601,0.0001224305,0.00004590578],"domain_scores_gemma":[0.9997612,0.00004978602,0.00004639602,0.00001848229,0.0000883495,0.0000359214],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00007778617,0.00003688046,0.003643719,0.00006086978,0.00001214566,0.00004511352,0.00002732164,0.0001184815,0.9926515,0.0000201447,0.0001011797,0.003204839],"study_design_scores_gemma":[0.00002089426,0.0008554602,0.3356749,0.00004411344,0.0001447637,0.0009992963,0.0005056456,0.003564804,0.6512585,0.0002541852,0.006630534,0.00004682819],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9819124,0.001141768,0.002133558,0.0001377056,0.00002042333,0.0001125419,0.0128367,0.0001087263,0.001596292],"genre_scores_gemma":[0.968231,0.001481224,0.007940438,0.0003101863,0.00003048202,0.000188224,0.01990763,0.00006975927,0.001841136],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001229508,"threshold_uncertainty_score":0.002303541,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01766112379120778,"score_gpt":0.2783043247795495,"score_spread":0.2606432009883418,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}