{"id":"W2471329520","doi":"10.1289/ehp408","title":"Comparison of Points of Departure for Health Risk Assessment Based on High-Throughput Screening Data","year":2016,"lang":"en","type":"article","venue":"Environmental Health Perspectives","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Confidence interval; Statistics; Relative risk; Medicine; Risk assessment; Absolute risk reduction; Mathematics; Toxicology; Computer science; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.04969398,0.001379073,0.00144512,0.004381363,0.0004224112,0.002727295,0.001980528,0.001676194,0.001640746],"category_scores_gemma":[0.1137442,0.0004465969,0.003280101,0.002143968,0.001373965,0.001843066,0.002158379,0.00276715,0.000507101],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002217742,"about_ca_system_score_gemma":0.001150527,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002415359,"about_ca_topic_score_gemma":0.001751111,"domain_scores_codex":[0.9701493,0.01735531,0.001862885,0.002586597,0.007489064,0.0005568744],"domain_scores_gemma":[0.7812736,0.1818003,0.01416404,0.01229102,0.00937433,0.001096651],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.01116965,0.001674654,0.1384281,0.003519655,0.004898454,0.0008135081,0.001066544,0.6575534,0.03409934,0.01916805,0.00534308,0.1222655],"study_design_scores_gemma":[0.0005239387,0.0100097,0.1876782,0.0004231767,0.001456721,0.001365488,0.000848073,0.6992229,0.05760177,0.02546069,0.01489453,0.000514876],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5993418,0.004815944,0.3737035,0.0008056302,0.0002374988,0.001395966,0.007663665,0.001827005,0.01020892],"genre_scores_gemma":[0.944394,0.0007684178,0.0460297,0.0003472364,0.0000460616,0.0007848344,0.006523079,0.0002195936,0.0008870236],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04969398,"threshold_uncertainty_score":0.26281,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03518876239074021,"score_gpt":0.3949004350537442,"score_spread":0.359711672663004,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}