{"id":"W2471484989","doi":"10.1182/blood.v124.21.sci-23.sci-23","title":"miRNAs, Immune Signaling, and Myelodysplastic Syndromes Pathogenesis","year":2014,"lang":"en","type":"article","venue":"Blood","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Biology; Myeloid; Cancer research; Immunology; Innate immune system; Bone marrow; Haematopoiesis; Myeloid leukemia; Myelodysplastic syndromes; Progenitor cell; RUNX1; Stem cell; Immune system; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001404123,0.0003827592,0.0002479437,0.000316164,0.0001708964,0.0004224795,0.0001563637,0.0003376649,0.0009838847],"category_scores_gemma":[0.00009280149,0.00008617478,0.0001747687,0.0002860986,0.0002374618,0.0001953394,0.0002450683,0.0004410757,0.0001815384],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002173736,"about_ca_system_score_gemma":0.0002102498,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004048667,"about_ca_topic_score_gemma":0.0004360063,"domain_scores_codex":[0.9999275,0.00001638585,0.000007036772,0.00002056541,0.00001548286,0.00001298257],"domain_scores_gemma":[0.9999487,0.000005452657,0.00002501195,0.000001551679,0.000006961217,0.00001227173],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.002898601,0.0004865861,0.0590768,0.004200657,0.000620255,0.01193629,0.0007390978,0.002010556,0.4153865,0.04343009,0.01472949,0.4444851],"study_design_scores_gemma":[0.0003451638,0.002511385,0.4411021,0.001442521,0.0008980938,0.03120937,0.001101183,0.005523285,0.06301794,0.03880566,0.4139206,0.0001227565],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.2521867,0.7315792,0.003171412,0.002398304,0.0003755856,0.00004722043,0.000453063,0.00009891923,0.009689622],"genre_scores_gemma":[0.7381395,0.2517097,0.001800578,0.0007762885,0.0005499712,0.00006777909,0.0004217859,0.00001060619,0.006523801],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0009838847,"threshold_uncertainty_score":0.003291428,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006568584418650612,"score_gpt":0.2259556582112611,"score_spread":0.2193870737926105,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}