{"id":"W2471545014","doi":"10.1021/acs.analchem.5b02568","title":"Desulfurization Activated Phosphorothioate DNAzyme for the Detection of Thallium","year":2015,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Deoxyribozyme; Chemistry; RNA; DNA; Cleave; Oligonucleotide; Thallium; Detection limit; Substrate (aquarium); Cleavage (geology); Cofactor; Biochemistry; Inorganic chemistry; Enzyme; Chromatography; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001871297,0.000104325,0.0001188258,0.000009919996,0.00004685401,0.00001100377,0.0001229224,0.0001502578,0.000001349106],"category_scores_gemma":[0.0003415471,0.00007327542,0.0001131364,0.0001311573,0.0001127005,0.000002995784,0.00004047133,0.0000639341,4.810136e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001789239,"about_ca_system_score_gemma":0.00004097867,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009255182,"about_ca_topic_score_gemma":0.000003214457,"domain_scores_codex":[0.9993502,0.00001206526,0.0001766893,0.0002070415,0.0001177752,0.0001362545],"domain_scores_gemma":[0.9993054,0.00002844412,0.00009593835,0.0002669228,0.0002415582,0.00006175148],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001322926,0.00002985243,0.00008287111,0.00001286468,0.00007148452,2.313597e-7,0.000004305228,0.0000284507,0.9976485,0.00001164994,0.0003046638,0.001672857],"study_design_scores_gemma":[0.0002219599,0.00007112409,0.00004748091,0.000006185833,0.00008191757,0.000004390653,0.00005618345,0.001787182,0.9912633,0.0001607555,0.006201787,0.00009772732],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8315701,0.0004441228,0.1655995,0.0005124366,0.00005915077,0.0002813671,0.00003277867,0.00006491343,0.001435617],"genre_scores_gemma":[0.9983026,0.0000512849,0.0006482503,0.00006351962,0.0001393249,0.00001119591,0.00007411122,0.00001231723,0.0006973529],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1667325,"threshold_uncertainty_score":0.2988085,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01988622809048489,"score_gpt":0.2833073395422591,"score_spread":0.2634211114517742,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}