{"id":"W2471684137","doi":"10.3390/cancers8070062","title":"Modulating Dickkopf-1: A Strategy to Monitor or Treat Cancer?","year":2016,"lang":"en","type":"review","venue":"Cancers","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"DKK1; Wnt signaling pathway; Biomarker; Context (archaeology); Cancer; Cancer research; Bioinformatics; Morphogenesis; Medicine; Biology; Signal transduction; Internal medicine; Cell biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001162473,0.0005691372,0.0009044563,0.0001017559,0.0001162145,0.00005358135,0.0005223406,0.0004376289,0.000404171],"category_scores_gemma":[0.00004275368,0.0003778066,0.0003165549,0.000256571,0.00006957525,0.000004622507,0.0001536186,0.0001535477,0.00008131262],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001122831,"about_ca_system_score_gemma":0.002706402,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001519148,"about_ca_topic_score_gemma":0.00008211943,"domain_scores_codex":[0.9978426,0.00006803992,0.0004888241,0.0008309232,0.0002134524,0.0005561479],"domain_scores_gemma":[0.9989053,0.00002662024,0.0002593148,0.0004721998,0.0000969183,0.0002396567],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005223872,0.000003318211,0.000005333663,0.001407038,0.0002326169,0.000008276841,0.00002134238,0.000106413,0.0005032686,0.000003116755,0.01687131,0.9807857],"study_design_scores_gemma":[0.0002565297,0.0001843129,0.000001574382,0.006785308,0.0001782276,0.000008617996,0.00001761931,0.000002583654,0.001155675,0.000004680242,0.9907451,0.0006598211],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003753728,0.9963779,0.0001432958,0.00001900636,0.0008861905,0.0006634917,0.000218836,0.0000356655,0.00128017],"genre_scores_gemma":[0.0003887033,0.9746481,0.0001801196,0.0001186919,0.002139515,0.001119627,0.000133099,0.000127068,0.02114506],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9801259,"threshold_uncertainty_score":0.9998674,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05476838547034811,"score_gpt":0.3621816001291741,"score_spread":0.3074132146588259,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}