{"id":"W2471984836","doi":"10.1182/blood.v122.21.880.880","title":"SNS01-T Exhibits Significant Anti-Tumoral Activity In Models Of Multiple Myeloma and Non-Hodgkins B Cell Lymphoma and Induces Cell Death In Malignant But Not Normal B Cells","year":2013,"lang":"en","type":"article","venue":"Blood","topic":"Polyamine Metabolism and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"","keywords":"Lymphoma; Cancer research; Mantle cell lymphoma; Transfection; Multiple myeloma; Apoptosis; Diffuse large B-cell lymphoma; B cell; Cell culture; Medicine; Biology; Molecular biology; Immunology; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022457,0.0003966504,0.000313845,0.0003540029,0.0001345094,0.0002006245,0.0002104283,0.0002662366,0.00134811],"category_scores_gemma":[0.00009511776,0.0001275023,0.0002849814,0.0001976275,0.0002137298,0.0001675925,0.0001116178,0.0005612177,0.0002186778],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002751849,"about_ca_system_score_gemma":0.0002838127,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001848499,"about_ca_topic_score_gemma":0.003202258,"domain_scores_codex":[0.9998581,0.00002932932,0.00000908346,0.00002164649,0.00005493964,0.00002690948],"domain_scores_gemma":[0.9998759,0.00002168578,0.00002791816,0.00001331478,0.00002195057,0.00003927297],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007627755,0.0004821467,0.0002473284,0.00006312702,0.00002385072,0.00002652403,0.00002008547,0.0002422226,0.9945028,0.00005647676,0.0001385003,0.003434198],"study_design_scores_gemma":[0.000110651,0.009081919,0.002653871,0.000006867461,0.00003990528,0.0001528928,0.00003000313,0.001064249,0.9853425,0.00002345432,0.001488817,0.000004813282],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954042,0.001180254,0.001520649,0.00005245015,0.00003080764,0.0000629016,0.0002565239,0.00007444348,0.001417603],"genre_scores_gemma":[0.9930651,0.000850943,0.001523201,0.00003593372,0.00001099788,0.00007315687,0.0007228139,0.00002145799,0.003696212],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001848499,"threshold_uncertainty_score":0.004509866,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0107900900894022,"score_gpt":0.2077290573226649,"score_spread":0.1969389672332627,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}