{"id":"W2472094702","doi":"10.1208/s12249-016-0543-x","title":"Clinically Relevant In Vitro Testing of Orally Inhaled Products—Bridging the Gap Between the Lab and the Patient","year":2016,"lang":"en","type":"review","venue":"AAPS PharmSciTech","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"Trudell Medical International (Canada)","funders":"","keywords":"Computer science; Medicine; Inhaler; Intensive care medicine; Medical physics; Risk analysis (engineering); Asthma; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003533463,0.001498049,0.002830999,0.002081174,0.0002588173,0.002284475,0.001683244,0.002383813,0.001871189],"category_scores_gemma":[0.003338741,0.000467447,0.001190198,0.001295808,0.001183882,0.001656112,0.0009888239,0.002676437,0.001477853],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006061037,"about_ca_system_score_gemma":0.001593971,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008462403,"about_ca_topic_score_gemma":0.00191271,"domain_scores_codex":[0.9978656,0.0006431212,0.0002105759,0.0001821034,0.0009939558,0.0001045997],"domain_scores_gemma":[0.9962389,0.002359489,0.0004857102,0.0001239255,0.0006748678,0.0001169815],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000168326,0.0002874277,0.0007482994,0.02403731,0.0001339392,0.0005676135,0.0001776377,0.0004081458,0.02526477,0.002645279,0.01266837,0.932893],"study_design_scores_gemma":[0.00006441325,0.001035023,0.00409053,0.01146759,0.0004045279,0.008246221,0.0005660889,0.0004239557,0.02448549,0.00327341,0.9458587,0.00008397618],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0006064159,0.996772,0.0007326026,0.000461927,0.0001753531,0.0000210465,0.00002174536,0.00001116586,0.001197815],"genre_scores_gemma":[0.005295418,0.9914613,0.001574653,0.000577886,0.0002946499,0.00002177041,0.0000690903,0.00000712979,0.0006981764],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003533463,"threshold_uncertainty_score":0.01868701,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08351969367200283,"score_gpt":0.3554135130200342,"score_spread":0.2718938193480313,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}