{"id":"W2472415732","doi":"10.1038/srep29171","title":"Overexpression of Bmi1 in Lymphocytes Stimulates Skeletogenesis by Improving the Osteogenic Microenvironment","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Key Research and Development Program of China; Chongqing Science and Technology Commission; Canadian Institutes of Health Research; Government of Jiangsu Province; Natural Science Foundation of Jiangsu Province; National Natural Science Foundation of China","keywords":"Mesenchymal stem cell; BMI1; Osteoblast; Genetically modified mouse; Chemistry; Transgene; Cell biology; Endocrinology; Internal medicine; Stem cell; Cancer research; Biology; In vitro; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000106318,0.0002643538,0.0001736673,0.000309476,0.0001078946,0.0002581442,0.000127672,0.0002536657,0.001925851],"category_scores_gemma":[0.00008323712,0.000120296,0.0002175851,0.0001474351,0.0001751484,0.0001706029,0.0002488913,0.0006209699,0.0005851508],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001257987,"about_ca_system_score_gemma":0.0001137187,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002039739,"about_ca_topic_score_gemma":0.0004204906,"domain_scores_codex":[0.9999043,0.00001286193,0.00000952987,0.00001779902,0.00002720686,0.00002833921],"domain_scores_gemma":[0.9998608,0.00001649617,0.00004669469,0.0000114425,0.00001151759,0.00005303604],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006036354,0.00001661976,0.0002167289,0.00001616035,0.000001319441,0.00001895511,0.000006278231,0.0000178524,0.9991258,0.00002525612,0.000009436072,0.0004851987],"study_design_scores_gemma":[0.00002964651,0.0003435558,0.008784491,0.000009788825,0.00001716307,0.0001894783,0.00004292931,0.0003674188,0.9884009,0.00004569929,0.001764492,0.000004380565],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950805,0.001113323,0.002220818,0.0001005958,0.00001828506,0.0000163381,0.0003001191,0.00007252368,0.001077488],"genre_scores_gemma":[0.9927792,0.001082352,0.002529735,0.00004622944,0.00001237982,0.00004191473,0.0004675757,0.00002675501,0.003013913],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001925851,"threshold_uncertainty_score":0.006442606,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004154013266893878,"score_gpt":0.2018954121226334,"score_spread":0.1977413988557395,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}