{"id":"W2472415732","doi":"10.1038/srep29171","title":"Overexpression of Bmi1 in Lymphocytes Stimulates Skeletogenesis by Improving the Osteogenic Microenvironment","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Key Research and Development Program of China; Chongqing Science and Technology Commission; Canadian Institutes of Health Research; Government of Jiangsu Province; Natural Science Foundation of Jiangsu Province; National Natural Science Foundation of China","keywords":"Mesenchymal stem cell; BMI1; Osteoblast; Genetically modified mouse; Chemistry; Transgene; Cell biology; Endocrinology; Internal medicine; Stem cell; Cancer research; Biology; In vitro; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004030634,0.0001051033,0.0001096968,0.00003425129,0.00008235512,0.00002678015,0.0001338702,0.00005470746,0.00004869146],"category_scores_gemma":[0.0001213411,0.00005774881,0.00008606219,0.00008030418,0.0002286947,0.000006754851,0.0001657139,0.00001477584,0.000003755954],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001503493,"about_ca_system_score_gemma":0.00008077911,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003882006,"about_ca_topic_score_gemma":0.000005778889,"domain_scores_codex":[0.9987813,0.0000495962,0.0003110225,0.0004652351,0.0001952173,0.0001976474],"domain_scores_gemma":[0.9990191,0.00001600389,0.0001907389,0.0006912511,0.00002753439,0.00005541488],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002117525,0.00005036995,0.01967196,0.000009596932,0.000006142985,0.000003916083,0.00001350681,0.00001320021,0.9715573,0.000001076106,0.003661152,0.004990574],"study_design_scores_gemma":[0.0002416279,0.00001919257,0.008325177,0.00002940977,0.00001136243,0.00001208934,0.00002243863,0.000004189549,0.9766567,0.000114494,0.01447361,0.00008972699],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937062,0.005502105,0.00007833228,0.00004371473,0.0004475942,0.0001562584,0.00001874402,0.000004224883,0.00004287214],"genre_scores_gemma":[0.9983544,0.00008440713,0.00006809111,0.00002356099,0.00003192536,0.00001530316,0.00003333632,0.0000103256,0.001378631],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01134678,"threshold_uncertainty_score":0.2354928,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004154013266893878,"score_gpt":0.2018954121226334,"score_spread":0.1977413988557395,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}