{"id":"W2472417552","doi":"10.5966/sctm.2015-0243","title":"Human Mesenchymal Stem Cells Impact Th17 and Th1 Responses Through a Prostaglandin E2 and Myeloid-Dependent Mechanism","year":2016,"lang":"en","type":"article","venue":"Stem Cells Translational Medicine","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Neurological Institute and Hospital; Concordia University; McGill University","funders":"National Institute of Neurological Disorders and Stroke; Case Western Reserve University","keywords":"Mesenchymal stem cell; Cell sorting; Cell biology; Peripheral blood mononuclear cell; CD14; Immune system; Cytokine; Stem cell; Prostaglandin E2; Cell; Biology; Immunology; Chemistry; Flow cytometry; In vitro; Endocrinology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001664859,0.0005547354,0.0009360915,0.0003608536,0.0003193057,0.00004289605,0.0001944598,0.0002907779,0.001277154],"category_scores_gemma":[0.00002840821,0.0003192929,0.000134598,0.0003143478,0.0006075081,0.0002955642,0.0000820112,0.0004104476,0.00005696285],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001467138,"about_ca_system_score_gemma":0.0003030839,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001960835,"about_ca_topic_score_gemma":0.00004350309,"domain_scores_codex":[0.9951578,0.0003649748,0.0008776039,0.0009495626,0.001845168,0.0008048279],"domain_scores_gemma":[0.997246,0.001050974,0.0002111062,0.0005177099,0.0002636754,0.0007105151],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001658945,0.0001461372,0.009679416,0.0005807726,0.0002658429,0.0003420986,0.002316903,0.000001760996,0.9701535,0.004016136,0.0008308903,0.01000767],"study_design_scores_gemma":[0.04599608,0.01307323,0.07705551,0.005744461,0.001083749,0.001921083,0.003168025,0.0003928232,0.8243492,0.01300935,0.01206193,0.002144552],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9789023,0.003736545,0.001792331,0.008172871,0.0003015853,0.002373295,0.0002116743,0.0001297081,0.004379712],"genre_scores_gemma":[0.9810693,0.0008443109,0.0003270763,0.0001967154,0.0004580095,0.00006433114,0.00001885634,0.0000795029,0.01694185],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1458042,"threshold_uncertainty_score":0.9999259,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05496171045127562,"score_gpt":0.3392187587794098,"score_spread":0.2842570483281341,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}