{"id":"W2472445905","doi":"10.1371/journal.pone.0158259","title":"Extensive Transcriptomic and Genomic Analysis Provides New Insights about Luminal Breast Cancers","year":2016,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"BC Cancer Agency; Australian Research Council; Cancer Research UK","keywords":"Transcriptome; Breast cancer; Computational biology; Biology; Bioinformatics; Medicine; Genetics; Cancer; Gene; Gene expression","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003049646,0.0002443199,0.0004041995,0.00114148,0.0002346393,0.0005817029,0.0001245564,0.0001688898,0.000928108],"category_scores_gemma":[0.0004520443,0.0001050178,0.0002675915,0.001058342,0.0002618226,0.0003291332,0.0003634456,0.0002799632,0.0002150632],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001719602,"about_ca_system_score_gemma":0.0002067313,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006730372,"about_ca_topic_score_gemma":0.001453102,"domain_scores_codex":[0.9997656,0.00005088063,0.00001642994,0.00007715479,0.00005756987,0.00003233973],"domain_scores_gemma":[0.9998341,0.00006030721,0.00004041898,0.00002644364,0.00002267853,0.0000160717],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004711729,0.00006718864,0.1252564,0.0003539267,0.0002154942,0.0003302882,0.0005494618,0.002779142,0.801694,0.001613736,0.0006828384,0.06598628],"study_design_scores_gemma":[0.000009239388,0.0001793859,0.9518169,0.00003877624,0.0001627068,0.0006780103,0.0005827593,0.006832287,0.02612143,0.00343593,0.01010946,0.00003318546],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9667813,0.003291408,0.02174709,0.0002644839,0.00001686923,0.0000287081,0.005371316,0.0001657281,0.002333255],"genre_scores_gemma":[0.9804214,0.002014345,0.0109419,0.0001820911,0.00005395807,0.00004739597,0.005658393,0.00003900166,0.000641479],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00114148,"threshold_uncertainty_score":0.003104806,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0153131673996984,"score_gpt":0.2110758664800077,"score_spread":0.1957626990803093,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}