{"id":"W2473421550","doi":"10.2174/1567205013666160502122933","title":"Pharmacological Management of Agitation and Aggression in Alzheimer's Disease: A Review of Current and Novel Treatments","year":2016,"lang":"en","type":"review","venue":"Current Alzheimer Research","topic":"Cholinesterase and Neurodegenerative Diseases","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"National Institute on Aging; Canadian Institutes of Health Research","keywords":"Aggression; Dementia; Medicine; Disease; Alzheimer's disease; Intervention (counseling); Intensive care medicine; Psychiatry; Lithium (medication); Psychomotor agitation; Clinical trial; Psychology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005890472,0.0003841039,0.001437677,0.0005035076,0.00004825428,0.00001140751,0.0001493984,0.0000688026,0.00007714864],"category_scores_gemma":[0.00015671,0.0002340839,0.0002540666,0.0005285001,0.000307465,0.00008631922,0.000334455,0.0003892154,0.000009591899],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000439615,"about_ca_system_score_gemma":0.0002453305,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001386285,"about_ca_topic_score_gemma":1.561294e-7,"domain_scores_codex":[0.996788,0.0005090572,0.0008816746,0.0006842179,0.0007920961,0.0003449665],"domain_scores_gemma":[0.9981541,0.0003182126,0.0003370125,0.0003384425,0.0004843178,0.0003679002],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0001272933,0.001187021,0.0001413763,0.0930903,0.0007927421,0.00003849464,0.00001169475,7.394986e-9,0.00001029066,0.00005547084,0.0009161594,0.9036291],"study_design_scores_gemma":[0.001858551,0.0001726145,0.0006402048,0.7417832,0.01003409,0.000009555644,0.000005069984,0.000004500116,0.00004695573,0.00002113681,0.2452006,0.0002234958],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005021125,0.9952825,0.000003053351,0.0001090948,0.0001424595,0.003628354,0.0002983676,0.000008628891,0.00002537708],"genre_scores_gemma":[0.0002523848,0.9986343,0.00001844559,0.00001809842,0.00009030455,0.0005857834,0.000359168,0.00003293318,0.000008561549],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9034057,"threshold_uncertainty_score":0.9545666,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4959715741649917,"score_gpt":0.5811006563981757,"score_spread":0.08512908223318394,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}