{"id":"W2473875060","doi":"10.1021/acs.langmuir.5b01533","title":"How Cell Concentrations Are Implicated in Cell Selectivity of Antimicrobial Peptides","year":2015,"lang":"en","type":"article","venue":"Langmuir","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Selectivity; Cell; Chemistry; Biophysics; Cell membrane; Lytic cycle; Peptide; Antimicrobial peptides; Antimicrobial; Membrane; Biochemistry; Biology; Immunology; Virus; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003473455,0.0003921019,0.0005257798,0.0003183712,0.0002789752,0.001154581,0.0004527345,0.000688931,0.000993061],"category_scores_gemma":[0.001925353,0.000329402,0.0002794187,0.0002754697,0.0006884069,0.001119786,0.0006248078,0.0006273863,0.0003502494],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005432446,"about_ca_system_score_gemma":0.000245839,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001261347,"about_ca_topic_score_gemma":0.0006287906,"domain_scores_codex":[0.9995819,0.00007882503,0.00002184123,0.0001149371,0.0001165974,0.0000859897],"domain_scores_gemma":[0.9989223,0.0006376968,0.0001706327,0.00009011394,0.0001271083,0.00005214226],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001855211,0.00006086297,0.007742011,0.0002150755,0.00002751137,0.0001959247,0.0001317302,0.01506227,0.9631673,0.006366844,0.0002178282,0.006627002],"study_design_scores_gemma":[0.00002724437,0.0002468356,0.01816759,0.00002932678,0.00007431364,0.0003376736,0.0002958021,0.1710009,0.7989322,0.007947445,0.002865899,0.00007480961],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9609736,0.001806296,0.03297677,0.0003549473,0.00005739504,0.0000425276,0.0002180423,0.0001266319,0.003443744],"genre_scores_gemma":[0.9961325,0.000477839,0.002855351,0.00005583161,0.000007367689,0.00002121641,0.00007064288,0.00001454786,0.0003647788],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001261347,"threshold_uncertainty_score":0.003941596,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01844167972060257,"score_gpt":0.2210567875937239,"score_spread":0.2026151078731214,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}