{"id":"W2473971766","doi":"10.1016/j.ijcard.2016.07.121","title":"Dual roles of calpain in facilitating Coxsackievirus B3 replication and prompting inflammation in acute myocarditis","year":2016,"lang":"en","type":"article","venue":"International Journal of Cardiology","topic":"Calpain Protease Function and Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Natural Science Foundation of China; Lawson Health Research Institute; National Science Foundation","keywords":"Medicine; Myocarditis; Inflammation; Coxsackievirus; Calpain; Immunology; Acute myocarditis; Dual (grammatical number); Virology; Enterovirus; Virus; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004977704,0.0005040754,0.0003588548,0.0004738891,0.0003398319,0.0008858382,0.0003704244,0.0008331283,0.0009300679],"category_scores_gemma":[0.0003555154,0.0002298711,0.000424178,0.000137211,0.0005788802,0.0007385052,0.0005621791,0.001034329,0.0001630146],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005993933,"about_ca_system_score_gemma":0.0002729532,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003391312,"about_ca_topic_score_gemma":0.000426834,"domain_scores_codex":[0.9996694,0.000066077,0.00003266547,0.00005016476,0.00005692696,0.0001246764],"domain_scores_gemma":[0.999741,0.00003147291,0.00004879057,0.00003114189,0.00003818296,0.000109474],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00220652,0.0001166629,0.002784276,0.0001127918,0.0000233588,0.0008193333,0.00007957879,0.00008411009,0.9884297,0.0009988764,0.00011862,0.004226183],"study_design_scores_gemma":[0.0005146593,0.002138251,0.1277039,0.0000768554,0.0002390036,0.005771086,0.0006521579,0.005197085,0.8496401,0.002832948,0.005193534,0.00004042204],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9787548,0.01559215,0.002965954,0.000601413,0.0001522943,0.0000393257,0.0001233569,0.00004414838,0.001726558],"genre_scores_gemma":[0.9949785,0.001909022,0.001838811,0.00008699668,0.0000674057,0.00002233706,0.00006363617,0.000006228698,0.001027168],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009300679,"threshold_uncertainty_score":0.004348993,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008149847907050943,"score_gpt":0.2673209158664079,"score_spread":0.259171067959357,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}