{"id":"W2474050077","doi":"10.4049/jimmunol.1600320","title":"Cytokine-Independent Detection of Antigen-Specific Germinal Center T Follicular Helper Cells in Immunized Nonhuman Primates Using a Live Cell Activation-Induced Marker Technique","year":2016,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":137,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Center for Research Resources; Yerkes National Primate Research Center, Emory University; National Institutes of Health; University of British Columbia; Center for AIDS Research, University of Washington; Emory University; National Institute of Allergy and Infectious Diseases; Bill and Melinda Gates Foundation","keywords":"Germinal center; Immunology; Cytokine; Antigen; Biology; B cell; Antibody","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001484058,0.0003048883,0.0006550606,0.0005903346,0.0002059397,0.00001163047,0.0006473389,0.0004419872,0.000415152],"category_scores_gemma":[0.00005779419,0.0001831443,0.0002697206,0.0002426918,0.0003580874,0.0002872112,0.0001412072,0.0006934198,0.00004571026],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002328059,"about_ca_system_score_gemma":0.0001492615,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001499275,"about_ca_topic_score_gemma":0.000006803785,"domain_scores_codex":[0.9964882,0.001637936,0.001117992,0.0001844548,0.00009980801,0.0004716215],"domain_scores_gemma":[0.9973757,0.0005868053,0.00120061,0.0005113378,0.0003118841,0.00001364573],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007810586,0.0003898877,0.0003751462,0.00001304967,0.000374522,0.00001244206,0.0009778793,0.000003994235,0.9861458,0.00001086593,0.00001195841,0.003873855],"study_design_scores_gemma":[0.004682968,0.0008377685,0.01303362,0.0002980717,0.00003390956,0.001032668,0.0007607419,0.00000109019,0.9766992,0.00005062615,0.002363722,0.0002056389],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884378,0.006711928,0.003561737,0.0001078106,0.0006660176,0.0004479258,0.000008277593,0.00001504853,0.00004350106],"genre_scores_gemma":[0.9943262,0.005180344,0.0001772105,0.00003075369,0.00002785313,0.00001074118,0.000002186467,0.00003867342,0.0002060217],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01265847,"threshold_uncertainty_score":0.7468409,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01340808697216612,"score_gpt":0.2373464680683413,"score_spread":0.2239383810961752,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}