{"id":"W2474399366","doi":"10.1186/s12864-016-2785-0","title":"Genome-wide association study of prolactin levels in blood plasma and cerebrospinal fluid","year":2016,"lang":"en","type":"article","venue":"BMC Genomics","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute on Aging; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; University of California, San Francisco; University of California, San Diego; National Institutes of Health; IXICO; Servier; University of California, Davis; Eisai; Genentech; Erasmus Medisch Centrum; Bundesministerium für Bildung und Forschung; Hjartavernd; Northern California Institute for Research and Education; Pfizer; Biogen; BioClinica; F. Hoffmann-La Roche; University of Pennsylvania; University of Southern California; Brigham Young University; Wellcome Trust; Synarc; National Heart, Lung, and Blood Institute; Novartis Pharmaceuticals Corporation; U.S. Department of Defense; Eli Lilly and Company; Bristol-Myers Squibb; Alzheimer's Association; Foundation for the National Institutes of Health; Medpace; Brigham and Women's Hospital; Alzheimer's Disease Neuroimaging Initiative; Medical Research Council; Meso Scale Diagnostics","keywords":"Prolactin; Cerebrospinal fluid; Biology; Lactation; Hormone; Immune system; Single-nucleotide polymorphism; Endocrinology; Internal medicine; Reproduction; Immunology; Genetics; Pregnancy; Medicine; Neuroscience; Gene; Genotype","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002203595,0.0006067812,0.001015315,0.001182493,0.0006143247,0.001100528,0.0007180681,0.001021099,0.00153952],"category_scores_gemma":[0.004922693,0.0003885955,0.00315391,0.003061873,0.0004011935,0.0003433671,0.0006164837,0.001058328,0.0001527787],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004121535,"about_ca_system_score_gemma":0.0004652173,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00955226,"about_ca_topic_score_gemma":0.008821968,"domain_scores_codex":[0.9975067,0.001018105,0.0002445065,0.0007825326,0.0002262428,0.0002219067],"domain_scores_gemma":[0.9963959,0.002093418,0.0007230936,0.0002877862,0.0002857597,0.0002139565],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003285851,0.00007376533,0.9603435,0.0003595016,0.02336635,0.0006842406,0.0001524918,0.0004972633,0.003491565,0.0001665552,0.000804882,0.006773996],"study_design_scores_gemma":[0.0002341222,0.0002558451,0.9795401,0.00008661821,0.01535514,0.0007129666,0.0001608677,0.001380672,0.00063584,0.0003420949,0.001268031,0.00002770249],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9815749,0.01433608,0.001164275,0.00055789,0.0001239134,0.00001235366,0.001632437,0.00004276551,0.0005553087],"genre_scores_gemma":[0.9969668,0.001386848,0.00059122,0.0001189052,0.00003900683,0.00001522345,0.0006820024,0.00001346972,0.0001866437],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00955226,"threshold_uncertainty_score":0.01899332,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02601154753162543,"score_gpt":0.2441640381292569,"score_spread":0.2181524905976315,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}