{"id":"W2475338014","doi":"10.3390/ijms17060990","title":"DNA Damage and Pulmonary Hypertension","year":2016,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"Pulmonary Hypertension Research and Treatments","field":"Medicine","cited_by":106,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Institut universitaire de cardiologie et de pneumologie de Québec","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"DNA damage; Pulmonary hypertension; Oxidative stress; Endothelial dysfunction; Vascular remodelling in the embryo; Internal medicine; Vascular resistance; Medicine; Pathogenesis; Heart failure; Cardiology; Cancer research; Pathology; Biology; DNA; Blood pressure; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002835666,0.0006577483,0.0009482915,0.001675779,0.0003629439,0.0008813659,0.000535886,0.001197308,0.004059201],"category_scores_gemma":[0.0006667232,0.0001869598,0.0004479512,0.001272358,0.0004283987,0.0009280877,0.0005687195,0.00122289,0.001499102],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005091318,"about_ca_system_score_gemma":0.001050132,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001167563,"about_ca_topic_score_gemma":0.001845554,"domain_scores_codex":[0.9997752,0.00004231207,0.00004028618,0.00003948517,0.00007931047,0.00002346124],"domain_scores_gemma":[0.999707,0.0001310348,0.00004962136,0.000007979556,0.00008025733,0.0000241751],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001161638,0.000104632,0.0007340013,0.02607097,0.0001763361,0.0005723952,0.0001542382,0.0003278129,0.002962599,0.004084918,0.03146438,0.9332315],"study_design_scores_gemma":[0.00002089892,0.0001690522,0.002628659,0.005050181,0.000170775,0.006301275,0.0001387092,0.00008185137,0.001196386,0.003058123,0.9811569,0.00002710253],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001737702,0.9984402,0.00008472672,0.0002551077,0.0001688301,0.000003850116,0.00001684225,0.000005706227,0.0008510661],"genre_scores_gemma":[0.001499986,0.9973661,0.0001065413,0.0001941313,0.0001616615,0.000005268171,0.00004102326,0.000001025313,0.0006242922],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004059201,"threshold_uncertainty_score":0.01357937,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06076882227503485,"score_gpt":0.3774952794827531,"score_spread":0.3167264572077183,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}