{"id":"W2475360113","doi":"10.1097/qad.0000000000001168","title":"Combination antiretroviral therapy and indoleamine 2,3-dioxygenase in HIV infections","year":2016,"lang":"en","type":"letter","venue":"AIDS","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Centre Hospitalier de l’Université de Montréal; Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Indoleamine 2,3-dioxygenase; Kynurenine; Kynurenine pathway; Immunology; Biology; Biochemistry; Tryptophan","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008395602,0.0002072021,0.000206755,0.0003751176,0.00007565821,0.00005774199,0.0001643308,0.0003140393,0.00009207721],"category_scores_gemma":[0.0001629251,0.0001643194,0.00005551468,0.0003020428,0.0001610272,0.0001869141,0.00004694828,0.0005831587,0.00008171337],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003578586,"about_ca_system_score_gemma":0.00003120594,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002270224,"about_ca_topic_score_gemma":0.000003086441,"domain_scores_codex":[0.9987361,0.0001706928,0.0001805673,0.0004220404,0.0001988717,0.0002916959],"domain_scores_gemma":[0.9993885,0.0002558522,0.00008062633,0.0002320289,0.00001469291,0.00002831132],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004349517,0.0002696719,0.01034735,0.00009065325,0.00001613084,0.0002826061,0.0002783898,5.065804e-7,0.1035141,0.00225552,0.7897828,0.09311888],"study_design_scores_gemma":[0.00429422,0.001059874,0.01440289,0.0001247042,0.000003099862,0.00003618901,0.00001467673,0.00002533212,0.06815355,0.003337936,0.9078825,0.0006649914],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8347809,0.0001949136,0.00008196311,0.1597852,0.0005397866,0.0004782014,0.00007787941,0.0001499591,0.003911267],"genre_scores_gemma":[0.6740688,0.0005031084,0.0000177321,0.3205016,0.0005960845,0.00003931917,0.00003240409,0.00004470662,0.004196234],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1607165,"threshold_uncertainty_score":0.6700749,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02490035206147964,"score_gpt":0.2503948115920827,"score_spread":0.225494459530603,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}