{"id":"W2475846115","doi":"10.3791/54228","title":"Human Primary Trophoblast Cell Culture Model to Study the Protective Effects of Melatonin Against Hypoxia/reoxygenation-induced Disruption","year":2016,"lang":"en","type":"article","venue":"Journal of Visualized Experiments","topic":"Pregnancy and preeclampsia studies","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Armand Frappier Museum","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada; Universitaire Stichting; Canadian Institutes of Health Research; Conselho Nacional de Desenvolvimento Científico e Tecnológico; March of Dimes Foundation","keywords":"Cytotrophoblast; Syncytiotrophoblast; Trophoblast; Biology; Hypoxia (environmental); Placenta; Melatonin; Cell biology; Andrology; Endocrinology; Internal medicine; Chemistry; Fetus; Medicine; Pregnancy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003636155,0.0002262035,0.0005624192,0.0001430127,0.0001866477,0.00001314529,0.000195484,0.00008491281,0.000007807527],"category_scores_gemma":[0.0001238316,0.0001113618,0.0002042614,0.0001777797,0.00004592211,0.000171609,0.00009910281,0.0002107984,0.000005055511],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002053875,"about_ca_system_score_gemma":0.00008158977,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004086421,"about_ca_topic_score_gemma":7.508869e-7,"domain_scores_codex":[0.9980581,0.0002546527,0.0006245199,0.0001967581,0.0006591764,0.0002067925],"domain_scores_gemma":[0.9986604,0.0000775424,0.0005684941,0.0002584508,0.0003097146,0.0001254206],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008422222,0.001652861,0.0005188363,0.00006611535,0.0004874319,0.00002713214,0.01902746,0.000010556,0.9758438,0.00002877016,0.0001978278,0.001296911],"study_design_scores_gemma":[0.0109703,0.004106591,0.02268158,0.0009180122,0.0002262676,0.00001367333,0.001789674,0.00002269823,0.9589225,0.0001576477,0.00003150634,0.0001595276],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940723,0.001104478,0.002028026,0.0001614976,0.0001501313,0.001795744,0.000003066492,0.00001500843,0.0006697433],"genre_scores_gemma":[0.9984506,0.00006875891,0.0007733662,0.0001919683,0.0001056339,0.0001319837,7.904703e-7,0.00002602533,0.0002508938],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02216275,"threshold_uncertainty_score":0.4541202,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03234139782274825,"score_gpt":0.3869755355391248,"score_spread":0.3546341377163766,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}