{"id":"W2475846115","doi":"10.3791/54228","title":"Human Primary Trophoblast Cell Culture Model to Study the Protective Effects of Melatonin Against Hypoxia/reoxygenation-induced Disruption","year":2016,"lang":"en","type":"article","venue":"Journal of Visualized Experiments","topic":"Pregnancy and preeclampsia studies","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Armand Frappier Museum","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada; Universitaire Stichting; Canadian Institutes of Health Research; Conselho Nacional de Desenvolvimento Científico e Tecnológico; March of Dimes Foundation","keywords":"Cytotrophoblast; Syncytiotrophoblast; Trophoblast; Biology; Hypoxia (environmental); Placenta; Melatonin; Cell biology; Andrology; Endocrinology; Internal medicine; Chemistry; Fetus; Medicine; Pregnancy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004990427,0.0004180314,0.0005615143,0.0004049809,0.0004820539,0.0004235211,0.0004039,0.0006050622,0.004133966],"category_scores_gemma":[0.0002501822,0.0002496045,0.0005043215,0.0004591516,0.0001984277,0.0002459096,0.0004012315,0.001197753,0.001778965],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004428312,"about_ca_system_score_gemma":0.0006004866,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003868799,"about_ca_topic_score_gemma":0.005623238,"domain_scores_codex":[0.9996029,0.00007192963,0.00003932813,0.00009476185,0.0001359568,0.0000551349],"domain_scores_gemma":[0.9998444,0.00003024111,0.00001941046,0.00004018885,0.00003802037,0.00002771827],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000590281,0.0001595728,0.00103585,0.0004468511,0.00003222994,0.0007884056,0.0003031081,0.0003191382,0.9882238,0.0008916688,0.001863792,0.00534512],"study_design_scores_gemma":[0.0001700754,0.002664891,0.009537583,0.0001269683,0.0002552443,0.004106196,0.0003668936,0.004282235,0.8758726,0.0005395653,0.1020302,0.00004749464],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7783769,0.03830207,0.1287245,0.001477214,0.001711303,0.002595152,0.01436794,0.001578682,0.03286613],"genre_scores_gemma":[0.8914028,0.01618574,0.05444859,0.000553716,0.0001552783,0.00275592,0.0120335,0.0001370427,0.0223274],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004133966,"threshold_uncertainty_score":0.01382953,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03234139782274825,"score_gpt":0.3869755355391248,"score_spread":0.3546341377163766,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}