{"id":"W2476189676","doi":"10.1111/ajt.13969","title":"Donor-Specific Antibodies Are Produced Locally in Ectopic Lymphoid Structures in Cardiac Allografts","year":2016,"lang":"en","type":"article","venue":"American Journal of Transplantation","topic":"Transplantation: Methods and Outcomes","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University; University of Manitoba","funders":"","keywords":"Medicine; Antibody; Immunology; Lymphatic system; Donor specific antibodies; Transplantation; Pathology; Kidney transplantation; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000408835,0.0001634013,0.0006129072,0.0004528155,0.00002286192,0.00001270983,0.00009469125,0.00004575959,0.00001831343],"category_scores_gemma":[0.00002769788,0.0001050321,0.0001430219,0.0003382234,0.0001346886,0.000189048,0.000002202319,0.000151761,0.000001961094],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009837567,"about_ca_system_score_gemma":0.0001049901,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009778843,"about_ca_topic_score_gemma":0.0001323788,"domain_scores_codex":[0.9984469,0.000222598,0.000616291,0.0001936055,0.0002944062,0.0002262246],"domain_scores_gemma":[0.9990997,0.0002468773,0.0003327501,0.0001234612,0.0001087072,0.00008847281],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001346675,0.00004857352,0.8557282,0.000100776,0.00005836996,0.0003692243,0.001495785,0.00003824538,0.06399499,0.00007521635,0.000009160763,0.07673476],"study_design_scores_gemma":[0.003038858,0.0003690363,0.9712583,0.0007223866,0.00008800975,0.00044297,0.0005374127,0.000001544711,0.02308949,0.0001906248,0.0001286947,0.0001327086],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920205,0.000498353,0.005486347,0.001448789,0.0002682807,0.0001832299,0.00002247141,0.00001196778,0.00006008745],"genre_scores_gemma":[0.9830583,0.00717209,0.009452689,0.0001335226,0.0001386615,0.000003876334,0.000008623284,0.00001670198,0.0000155768],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.11553,"threshold_uncertainty_score":0.4283084,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01390802191663514,"score_gpt":0.2860496364316107,"score_spread":0.2721416145149756,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}