{"id":"W2477072027","doi":"10.1021/acs.biochem.6b00542","title":"Enhanced Nitrite Reductase Activity and Its Correlation with Oxygen Affinity in Hemoglobin Bis-Tetramers","year":2016,"lang":"en","type":"article","venue":"Biochemistry","topic":"Hemoglobin structure and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Canadian Blood Services","keywords":"Hemoglobin; Chemistry; Nitrite reductase; Nitrite; Oxygen; Biochemistry; Enzyme; Nitrate reductase; Organic chemistry; Nitrate","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009431833,0.0001803805,0.0001327062,0.00003147461,0.00004776569,0.00001404781,0.00008139948,0.0002461614,0.00002407374],"category_scores_gemma":[0.0001186052,0.0001344667,0.00003284341,0.0001236681,0.0000777295,0.00001087754,0.00004682838,0.00009574135,0.000004658183],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004096677,"about_ca_system_score_gemma":0.0001080682,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001201513,"about_ca_topic_score_gemma":0.00001291749,"domain_scores_codex":[0.9990602,0.00002961112,0.0001328617,0.0004428043,0.0001095316,0.0002249939],"domain_scores_gemma":[0.9995006,0.00001633515,0.00008081088,0.0002427215,0.00005790049,0.0001015851],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003779206,0.0000341356,0.001364411,0.00002607192,0.00001826238,0.000003404445,0.00001139795,0.000002844663,0.9921896,0.000004882571,0.0002700986,0.005696899],"study_design_scores_gemma":[0.001061227,0.0001109159,0.006402716,0.00004297103,0.00001154721,0.00003031939,0.00003051916,0.00001275478,0.9914132,0.00001184044,0.0006523444,0.0002196666],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972052,0.0002802887,0.0008993475,0.0001568125,0.00007741374,0.0001366595,0.00004260071,0.00001750968,0.001184172],"genre_scores_gemma":[0.9986104,0.0001225758,0.0001571671,0.00005605194,0.0001492132,0.00001701557,0.0000598956,0.00001636132,0.0008113426],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005477233,"threshold_uncertainty_score":0.5483394,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005332656972488408,"score_gpt":0.2142067119316057,"score_spread":0.2088740549591173,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}