{"id":"W2477682166","doi":"10.1158/1538-7445.am2016-3261","title":"Abstract 3261: Impact of CTLA-4 blockade in conjunction with metronomic chemotherapy on preclinical breast cancer growth","year":2016,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Medicine; Gemcitabine; Cyclophosphamide; Paclitaxel; Chemotherapy; Breast cancer; Regimen; Oncology; Cancer; Bolus (digestion); Internal medicine; Pharmacology; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001967394,0.0005922164,0.0005236676,0.0003186041,0.0001732446,0.0002645454,0.00029593,0.0003594305,0.003508618],"category_scores_gemma":[0.0001549756,0.0001773525,0.000284946,0.000215765,0.0002105538,0.0002244776,0.0001870313,0.001170997,0.000775489],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004020448,"about_ca_system_score_gemma":0.0004693361,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001498901,"about_ca_topic_score_gemma":0.001838969,"domain_scores_codex":[0.9997908,0.00005002585,0.0000168225,0.00002718178,0.00004968395,0.00006549001],"domain_scores_gemma":[0.9998324,0.00003232618,0.00003018289,0.00002264534,0.00001505257,0.00006743566],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002940914,0.002041597,0.000362978,0.00009127824,0.00001669781,0.0001002508,0.00002941701,0.0007427375,0.9876812,0.0001770022,0.0006429016,0.005173028],"study_design_scores_gemma":[0.0002573834,0.01166139,0.00335232,0.00001101842,0.00002322875,0.0001824843,0.00002458711,0.001894983,0.9802829,0.00004428727,0.002258296,0.000007105968],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993112,0.001211233,0.0006411629,0.0002779699,0.0001028798,0.0001212828,0.001143678,0.0001522029,0.003237706],"genre_scores_gemma":[0.9916221,0.0007006426,0.001020765,0.00007602869,0.00001892838,0.0001300071,0.001627009,0.00003452076,0.004769989],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003508618,"threshold_uncertainty_score":0.01173753,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06897503347927765,"score_gpt":0.4399733878566051,"score_spread":0.3709983543773275,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}