{"id":"W2477810116","doi":"10.1158/1538-7445.am2016-2206","title":"Abstract 2206: Development and characterization of an injectable copper clioquinol formulation: repurposing of a topical antifungal for treatment of cancer","year":2016,"lang":"en","type":"article","venue":"Cancer Research","topic":"Metal complexes synthesis and properties","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Spinal Cord Injury BC","funders":"","keywords":"Liposome; Pharmacokinetics; Clioquinol; Pharmacology; Bioavailability; Chemistry; Antifungal; Medicine; Drug; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002368565,0.0002707679,0.0001497187,0.0002319946,0.00009912342,0.0002127721,0.00019155,0.0002479628,0.001042075],"category_scores_gemma":[0.0002208206,0.00009121427,0.0001781563,0.0001446443,0.0001330469,0.0001408371,0.00009325969,0.0002148421,0.0004680318],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001989609,"about_ca_system_score_gemma":0.0001758317,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007057425,"about_ca_topic_score_gemma":0.0005212933,"domain_scores_codex":[0.9999146,0.00001624039,0.000006619498,0.00001838871,0.00003241365,0.00001162858],"domain_scores_gemma":[0.9998965,0.00001008865,0.00002671609,0.000006638989,0.00003462311,0.00002550072],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003421336,0.00002585514,0.00005152448,0.00002825331,0.000002065605,0.00003858692,0.000009910528,0.00006351282,0.9977088,0.00002300455,0.00003997841,0.001974273],"study_design_scores_gemma":[0.00002066022,0.0008273807,0.001440209,0.000008558446,0.00001613046,0.0002186146,0.00001135015,0.001044881,0.9924248,0.00001494578,0.003966594,0.000005799689],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.967856,0.00361478,0.0236555,0.0001768332,0.00006128853,0.0004619498,0.0007212521,0.0001840199,0.003268382],"genre_scores_gemma":[0.9749767,0.001464422,0.01707031,0.0001028546,0.00002173973,0.0001193107,0.0007965313,0.00007365316,0.005374366],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001042075,"threshold_uncertainty_score":0.003486037,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.211338489831226,"score_gpt":0.425844551729004,"score_spread":0.214506061897778,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}