{"id":"W2478854878","doi":"10.4049/jimmunol.1600847","title":"T Cell Fates Zipped Up: How the Bach2 Basic Leucine Zipper Transcriptional Repressor Directs T Cell Differentiation and Function","year":2016,"lang":"en","type":"review","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences","keywords":"Zipper; Leucine zipper; Cell biology; Function (biology); Repressor; Chemistry; Cellular differentiation; Cell; Transcription factor; Biology; Gene; Biochemistry; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002711585,0.0004303083,0.0006340191,0.0008741554,0.0001781904,0.0006123512,0.0004364465,0.0004554125,0.001475826],"category_scores_gemma":[0.0002173746,0.0001493326,0.0002449896,0.0006716029,0.0003535138,0.0008622663,0.000446954,0.0009225344,0.001136653],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004563864,"about_ca_system_score_gemma":0.0005346645,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004517098,"about_ca_topic_score_gemma":0.0008175327,"domain_scores_codex":[0.9999264,0.00001064553,0.000009861522,0.00001414503,0.00002692723,0.00001195967],"domain_scores_gemma":[0.999935,0.00001725867,0.00001220543,0.000002764557,0.00001921934,0.00001358108],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001155361,0.00002539747,0.0002761125,0.006486959,0.00006176675,0.0003428578,0.00007876617,0.0003333292,0.02099706,0.007707804,0.02134649,0.9422278],"study_design_scores_gemma":[0.00001775064,0.00009890307,0.00159982,0.0008025625,0.00006860689,0.002220537,0.0000692297,0.000141002,0.003897788,0.002956967,0.9881071,0.00001965272],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005149647,0.9968824,0.00033032,0.0002741574,0.00022051,0.000003546561,0.00001662561,0.00001337452,0.001744015],"genre_scores_gemma":[0.003672227,0.9938402,0.0003933661,0.0002277206,0.0002422351,0.000006551223,0.00004201983,0.000003284425,0.001572422],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001475826,"threshold_uncertainty_score":0.004937053,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02299656806340157,"score_gpt":0.239178905695546,"score_spread":0.2161823376321445,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}