{"id":"W2478854878","doi":"10.4049/jimmunol.1600847","title":"T Cell Fates Zipped Up: How the Bach2 Basic Leucine Zipper Transcriptional Repressor Directs T Cell Differentiation and Function","year":2016,"lang":"en","type":"review","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences","keywords":"Zipper; Leucine zipper; Cell biology; Function (biology); Repressor; Chemistry; Cellular differentiation; Cell; Transcription factor; Biology; Gene; Biochemistry; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0009402865,0.0004954324,0.001188821,0.000325088,0.0004885776,0.00005240716,0.0005283827,0.0006612577,0.001431549],"category_scores_gemma":[0.0001047709,0.0002268687,0.000573868,0.0001564936,0.0003905068,0.0002883549,0.0001017913,0.001562657,0.0003219517],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001197059,"about_ca_system_score_gemma":0.0001566221,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001398096,"about_ca_topic_score_gemma":0.000002258801,"domain_scores_codex":[0.9960729,0.002192881,0.0009649643,0.0002823553,0.00009318972,0.0003936694],"domain_scores_gemma":[0.9963637,0.001038375,0.001791103,0.0005098987,0.0002746377,0.00002230144],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002625654,0.0003667377,0.00001208235,0.001303144,0.003284556,0.00000441559,0.0009620978,0.000001543407,0.3600343,0.0002762491,0.05504217,0.5760871],"study_design_scores_gemma":[0.001741298,0.00064061,0.0002668627,0.001160643,0.001837232,0.001094592,0.0002730514,6.831533e-7,0.005180301,0.00005302353,0.9875011,0.0002506168],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001704673,0.9833756,0.0005716344,0.001067192,0.01229209,0.0004491145,0.00001295922,0.00002773307,0.0004989814],"genre_scores_gemma":[0.01372052,0.9483037,0.000003323709,0.0001130353,0.0002481383,0.00002211491,0.00008652242,0.00004975192,0.03745288],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9324589,"threshold_uncertainty_score":0.9994813,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02299656806340157,"score_gpt":0.239178905695546,"score_spread":0.2161823376321445,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}