{"id":"W2479615790","doi":"10.1158/1538-7445.am2016-5056","title":"Abstract 5056: RET-mediated invasion in three-dimensional microenvironment models","year":2016,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Glial cell line-derived neurotrophic factor; Cancer research; Biology; Receptor tyrosine kinase; Metastasis; Integrin; Cell biology; Stromal cell; Tumor microenvironment; PI3K/AKT/mTOR pathway; Signal transduction; Neurotrophic factors; Receptor; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001432768,0.0005480489,0.0002803689,0.0005156354,0.0002018783,0.0004756947,0.0003202,0.0004841978,0.001126595],"category_scores_gemma":[0.00008270251,0.0002276125,0.0004650668,0.000260822,0.0002161049,0.0002365705,0.0003842481,0.0004718385,0.0003229801],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004342601,"about_ca_system_score_gemma":0.0002859178,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003636396,"about_ca_topic_score_gemma":0.003855105,"domain_scores_codex":[0.999867,0.00001573379,0.000007239281,0.00002414666,0.00005919886,0.00002667363],"domain_scores_gemma":[0.9999113,0.00001930259,0.00002815799,0.000008920273,0.00001438276,0.00001789933],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001547453,0.0001800754,0.0009385627,0.0001477355,0.00003140073,0.0004169994,0.00009187421,0.04952191,0.9412717,0.003203658,0.0003915302,0.003649765],"study_design_scores_gemma":[0.00004363305,0.0004521658,0.005155199,0.00002831521,0.00004831812,0.0005615819,0.00009501295,0.5864263,0.398973,0.001027203,0.007132373,0.00005689065],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9366397,0.001452714,0.05177797,0.0002014998,0.00006846513,0.0001029349,0.001738257,0.0003830834,0.007635406],"genre_scores_gemma":[0.9644018,0.001088246,0.02765834,0.00003642938,0.00001284882,0.0001597136,0.001242107,0.00005808677,0.005342498],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003636396,"threshold_uncertainty_score":0.007230461,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1289440732197326,"score_gpt":0.3707742373397571,"score_spread":0.2418301641200244,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}