{"id":"W2479703093","doi":"10.4049/jimmunol.1502486","title":"A Histone Methyltransferase ESET Is Critical for T Cell Development","year":2016,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Aging","funders":"","keywords":"Histone methyltransferase; Methyltransferase; Cell biology; Chemistry; Histone; Biology; Biochemistry; Methylation; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001152511,0.0003534273,0.0002562565,0.0002468459,0.0002827629,0.0003401228,0.0002654253,0.0003187398,0.002165616],"category_scores_gemma":[0.0001484879,0.0001724933,0.0002640736,0.0002047213,0.0002308258,0.0002527659,0.0003762105,0.0004775105,0.000864551],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003174192,"about_ca_system_score_gemma":0.0002179831,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004302416,"about_ca_topic_score_gemma":0.0006318655,"domain_scores_codex":[0.9998753,0.00001208203,0.00001117621,0.00003882633,0.00003722333,0.000025417],"domain_scores_gemma":[0.9998757,0.00001045255,0.00004209326,0.00001063462,0.00002354616,0.00003754117],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001047608,0.000008993696,0.00104754,0.00005874058,0.00001091255,0.0001644796,0.00001423825,0.00008262912,0.9921778,0.0002378379,0.0001328989,0.005959203],"study_design_scores_gemma":[0.00001319726,0.0001093871,0.01771249,0.00001428999,0.00003079878,0.0008710927,0.00003214111,0.0006365898,0.9663734,0.0002092792,0.01398909,0.000008242013],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9464602,0.01524149,0.02785812,0.0003969459,0.0002077704,0.00006210039,0.002633863,0.0007572746,0.006382199],"genre_scores_gemma":[0.9831632,0.002656251,0.004851016,0.00009900353,0.00002852629,0.00002409896,0.002238174,0.0000529473,0.006886759],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002165616,"threshold_uncertainty_score":0.007244706,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01534776757468961,"score_gpt":0.2963840083739835,"score_spread":0.2810362407992939,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}