{"id":"W2480664037","doi":"10.1016/b978-0-12-396965-1.00004-2","title":"B Cells, the Bursa of Fabricius and the Generation of Antibody Repertoires","year":2013,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":51,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Bursa of Fabricius; Biology; Germinal center; CD40; Cell biology; Mesenchyme; Antibody; B cell; Lymphatic system; Immunology; Genetics; Spleen; Mesenchymal stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002134677,0.0003103311,0.0001912584,0.0003438652,0.0003179592,0.001084736,0.0003244999,0.0004911314,0.00418466],"category_scores_gemma":[0.0001666644,0.0001567922,0.0001087285,0.0002808127,0.001024133,0.0008019686,0.0005217656,0.0008692581,0.0009597528],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005423899,"about_ca_system_score_gemma":0.0002709719,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007658562,"about_ca_topic_score_gemma":0.001191222,"domain_scores_codex":[0.99993,0.00001314733,0.000002967776,0.00001547504,0.00002299415,0.0000153663],"domain_scores_gemma":[0.9999663,0.00001437936,0.000005143308,0.000002444671,0.000003559715,0.000008189549],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002223441,0.00005517879,0.0008451384,0.0005831374,0.00002074066,0.0005635006,0.001636315,0.001345552,0.07099514,0.4215885,0.03223177,0.4699127],"study_design_scores_gemma":[0.00001285063,0.00007481589,0.001541123,0.0002079004,0.000008904341,0.0006794254,0.000326684,0.0002044098,0.005019102,0.08509983,0.9068131,0.00001188524],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"other","genre_scores_codex":[0.06314746,0.494335,0.01018139,0.005353182,0.002019353,0.00002580973,0.0001124964,0.0001252806,0.4247],"genre_scores_gemma":[0.327039,0.1649883,0.009983139,0.001713626,0.001236565,0.00005456277,0.0001523641,0.00007660464,0.4947558],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.00418466,"threshold_uncertainty_score":0.0139991,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01410873023946249,"score_gpt":0.2164046989602087,"score_spread":0.2022959687207462,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}