{"id":"W2480735601","doi":"10.1128/aac.00732-16","title":"The <i>RTA3</i> Gene, Encoding a Putative Lipid Translocase, Influences the Susceptibility of Candida albicans to Fluconazole","year":2016,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Candida albicans; Translocase; Biology; Gene; Azole; ATP-binding cassette transporter; Fluconazole; Corpus albicans; Gene product; Molecular biology; Microbiology; Transporter; Genetics; Gene expression; Chromosomal translocation; Antifungal","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009742391,0.0003388759,0.000202352,0.0002800745,0.0001677655,0.0004301059,0.0001956674,0.0003189809,0.001417624],"category_scores_gemma":[0.0002132473,0.0001582638,0.0002675805,0.000174878,0.0003477013,0.0001305687,0.0001901609,0.0005000338,0.0003474094],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004061263,"about_ca_system_score_gemma":0.0002446957,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00195448,"about_ca_topic_score_gemma":0.002108196,"domain_scores_codex":[0.999838,0.00003167758,0.00001364508,0.00003326538,0.00004291935,0.00004052695],"domain_scores_gemma":[0.9998246,0.00005427507,0.00004226205,0.00001219196,0.00001458774,0.00005213697],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008199948,0.000009939169,0.0002664672,0.00000464007,0.000002123026,0.00007255709,0.000006801397,0.00003352583,0.9991475,0.00003261555,0.00001815468,0.0003236827],"study_design_scores_gemma":[0.00003034717,0.0001396171,0.03018112,0.000007643337,0.00003416837,0.001342817,0.00007843447,0.002911472,0.9635764,0.00009893737,0.001583338,0.0000157607],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973816,0.0001623376,0.0009891399,0.0000634892,0.00001139471,0.00001037736,0.0002772195,0.00005281667,0.001051559],"genre_scores_gemma":[0.9982856,0.0000851583,0.0005839634,0.00004195547,0.000004487084,0.00000709711,0.0002089308,0.00003339936,0.0007493233],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00195448,"threshold_uncertainty_score":0.004742444,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01455674097592376,"score_gpt":0.278254674624689,"score_spread":0.2636979336487653,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}