{"id":"W2480868774","doi":"10.1038/ncomms12309","title":"A critical role for NF2 and the Hippo pathway in branching morphogenesis","year":2016,"lang":"en","type":"article","venue":"Nature Communications","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"National Cancer Institute; Krembil Foundation; Canadian Institutes of Health Research; March of Dimes Foundation; U.S. Department of Defense","keywords":"Morphogenesis; Cell biology; Biology; Branching (polymer chemistry); Hippo signaling pathway; Genetics; Signal transduction; Chemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000118685,0.0004070817,0.000130927,0.0002166841,0.0003604098,0.0004225129,0.0001637825,0.000337977,0.001044927],"category_scores_gemma":[0.0001121637,0.0001104188,0.0001744861,0.0000899952,0.000395517,0.000472421,0.0003623269,0.0003026077,0.0002037109],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004289377,"about_ca_system_score_gemma":0.0003299831,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007050998,"about_ca_topic_score_gemma":0.001148892,"domain_scores_codex":[0.9999114,0.000009639682,0.000005531097,0.00001960652,0.00002520093,0.00002871514],"domain_scores_gemma":[0.9999033,0.000009105945,0.00002898957,0.000007783062,0.00001201172,0.00003874644],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001264553,0.000007709326,0.0008337598,0.00003948114,0.00000578127,0.0002322417,0.00002457217,0.0001365811,0.9958746,0.0008619478,0.00003445512,0.00182247],"study_design_scores_gemma":[0.00004632174,0.0003040743,0.04078521,0.00003214647,0.00002949445,0.002412845,0.0001542882,0.002645989,0.9383935,0.001838239,0.01333205,0.00002584601],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9807772,0.00786385,0.005522609,0.0002690418,0.00002763887,0.00001163957,0.000193372,0.0001236102,0.005211066],"genre_scores_gemma":[0.9951298,0.001255005,0.00137803,0.0000245873,0.00001417935,0.000009507603,0.0001684545,0.00001282709,0.002007507],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001044927,"threshold_uncertainty_score":0.003495634,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01172758571781008,"score_gpt":0.2852033493888997,"score_spread":0.2734757636710896,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}