{"id":"W2482099207","doi":"10.1139/bcb-2015-0165","title":"Fructated apolipoprotein A-I exacerbates cellular senescence in human umbilical vein endothelial cells accompanied by impaired insulin secretion activity and embryo toxicity","year":2016,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Diet, Metabolism, and Disease","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Internal medicine; Endocrinology; Apolipoprotein B; Umbilical vein; Insulin; Chemistry; Glycation; Lipoprotein; Biology; Diabetes mellitus; Biochemistry; Cholesterol; Medicine; In vitro","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001646052,0.0003119947,0.0002450405,0.0001589743,0.0001072041,0.0002147241,0.0001416401,0.0002079923,0.0005108785],"category_scores_gemma":[0.0001061989,0.0001399605,0.0002941778,0.0001329184,0.0001094393,0.0001287691,0.0001573977,0.000436899,0.0001491783],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001450902,"about_ca_system_score_gemma":0.0001150673,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007380089,"about_ca_topic_score_gemma":0.0004318587,"domain_scores_codex":[0.9998665,0.00003408999,0.00002112473,0.00002167863,0.00002787427,0.00002875781],"domain_scores_gemma":[0.9999154,0.00001286984,0.00002427056,0.00001554848,0.0000122893,0.00001961502],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002328968,0.00004630278,0.0002425042,0.00001677582,0.000008688012,0.0001113585,0.00002551971,0.00002028328,0.9984953,0.00003197603,0.0000235616,0.0007447235],"study_design_scores_gemma":[0.00003380812,0.001684786,0.01376065,0.000007914839,0.00003995596,0.0006495895,0.00008115709,0.001050239,0.9812202,0.00005336292,0.001410636,0.000007535852],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979784,0.0008779069,0.0005529417,0.00003294412,0.0000190238,0.00001014106,0.00007905476,0.00002271466,0.0004269592],"genre_scores_gemma":[0.9974837,0.0006104541,0.0005407165,0.00006127521,0.000007514046,0.00001977678,0.0002268051,0.000007025475,0.001042711],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007380089,"threshold_uncertainty_score":0.001709044,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007949380132416427,"score_gpt":0.2340220702576277,"score_spread":0.2260726901252113,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}