{"id":"W2482579890","doi":"10.2337/db16-0114","title":"Impaired Cardiolipin Biosynthesis Prevents Hepatic Steatosis and Diet-Induced Obesity","year":2016,"lang":"en","type":"article","venue":"Diabetes","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"Shared Health; University of Manitoba; Children's Hospital Research Institute of Manitoba","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; Research Manitoba; Barth Syndrome Foundation","keywords":"Cardiolipin; Insulin resistance; Endocrinology; Steatosis; Internal medicine; Inner mitochondrial membrane; Mitochondrion; Biology; Fatty liver; Steatohepatitis; Beta oxidation; Type 2 diabetes; Insulin; Diabetes mellitus; Metabolism; Phospholipid; Medicine; Biochemistry; Membrane","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001419371,0.0004026539,0.0004179177,0.0005273844,0.0002073828,0.0003765325,0.0002884934,0.0003437346,0.001168518],"category_scores_gemma":[0.0001989762,0.0001703666,0.0001653291,0.0002587479,0.0003619555,0.0002962699,0.0002662696,0.0009002794,0.0003691878],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002578761,"about_ca_system_score_gemma":0.0003365637,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007887937,"about_ca_topic_score_gemma":0.001285556,"domain_scores_codex":[0.9998741,0.00001984012,0.00001507903,0.00002693224,0.00002568327,0.00003833791],"domain_scores_gemma":[0.999725,0.0000227425,0.00009578714,0.00003054442,0.00002433484,0.0001015802],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001494047,0.0003010086,0.0003107408,0.00003334419,0.00001106448,0.00002711176,0.00002047421,0.00008875907,0.9940508,0.0001476725,0.00009485008,0.003420251],"study_design_scores_gemma":[0.0002192856,0.001896614,0.006841838,0.00001716161,0.00004021559,0.0001294664,0.00006740877,0.001072861,0.9871957,0.0001716841,0.002337135,0.0000105954],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955591,0.0005904364,0.002252548,0.0001926653,0.00003600335,0.00002125884,0.0003034866,0.0002113856,0.0008331917],"genre_scores_gemma":[0.9938796,0.0006024915,0.001594997,0.00008826806,0.00001302182,0.00003436085,0.0005733678,0.00007543016,0.003138372],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001168518,"threshold_uncertainty_score":0.003909111,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01078285162964025,"score_gpt":0.2189201467513318,"score_spread":0.2081372951216915,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}