{"id":"W2482579890","doi":"10.2337/db16-0114","title":"Impaired Cardiolipin Biosynthesis Prevents Hepatic Steatosis and Diet-Induced Obesity","year":2016,"lang":"en","type":"article","venue":"Diabetes","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"Shared Health; University of Manitoba; Children's Hospital Research Institute of Manitoba","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; Research Manitoba; Barth Syndrome Foundation","keywords":"Cardiolipin; Insulin resistance; Endocrinology; Steatosis; Internal medicine; Inner mitochondrial membrane; Mitochondrion; Biology; Fatty liver; Steatohepatitis; Beta oxidation; Type 2 diabetes; Insulin; Diabetes mellitus; Metabolism; Phospholipid; Medicine; Biochemistry; Membrane","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001197319,0.0001269294,0.0001691125,0.00003168009,0.00006236594,0.00001088195,0.00008197168,0.0001911978,0.00004202525],"category_scores_gemma":[0.0001797668,0.00008952984,0.00007925144,0.00003942485,0.00004755968,0.000003783107,0.00007602477,0.00003734424,0.00002757946],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007856769,"about_ca_system_score_gemma":0.0000174445,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006629592,"about_ca_topic_score_gemma":0.000005578478,"domain_scores_codex":[0.9991653,0.0001289618,0.000126197,0.0002991744,0.00006282193,0.000217556],"domain_scores_gemma":[0.9995365,0.00003867278,0.00004446923,0.0002630179,0.0000276966,0.00008964472],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002791897,0.00002432063,0.1383808,0.00001139775,0.00005028979,4.853361e-7,0.00001132123,4.374338e-8,0.8555712,0.00001050366,0.000529326,0.005382335],"study_design_scores_gemma":[0.0004166229,0.0003774505,0.03245258,0.00002575157,0.00003291304,0.000001340184,0.00001033087,0.000004026092,0.961915,0.00007811098,0.004519469,0.0001664067],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987781,0.0002629325,0.00009801362,0.0001595075,0.0002880113,0.0001406168,0.00003156382,0.0000192843,0.0002219573],"genre_scores_gemma":[0.9988625,0.0001372938,0.0001490966,0.0001872911,0.0002020799,0.00003059149,0.00001417745,0.00001453325,0.000402454],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1063438,"threshold_uncertainty_score":0.3650921,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01078285162964025,"score_gpt":0.2189201467513318,"score_spread":0.2081372951216915,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}