{"id":"W2483129460","doi":"10.1083/jcb.201603105","title":"Syntaxin-17 delivers PINK1/parkin-dependent mitochondrial vesicles to the endolysosomal system","year":2016,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":243,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research","keywords":"PINK1; Endosome; Cell biology; Syntaxin; Retromer; Lysosome; Parkin; Vacuole; Mitophagy; Endocytic cycle; Mitochondrion; Biology; Lipid bilayer fusion; Vesicle; SNARE complex; Vesicle fusion; Rab; Biochemistry; Synaptic vesicle; Autophagy; Endocytosis; Cell; Cytoplasm; GTPase; Membrane; Intracellular","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004656814,0.0001391719,0.0001808488,0.00004382377,0.0001137634,0.00001003118,0.0005225698,0.0001366168,0.00003763698],"category_scores_gemma":[0.00002935186,0.00006101164,0.0001651334,0.00004646661,0.0001046813,0.000003969672,0.00006281197,0.0001145661,0.00003398411],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002992572,"about_ca_system_score_gemma":0.00006902606,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001587726,"about_ca_topic_score_gemma":0.00004616053,"domain_scores_codex":[0.9988958,0.0002409927,0.0003525604,0.0001437027,0.0001308889,0.0002361102],"domain_scores_gemma":[0.9991794,0.00006536531,0.0002439421,0.0002977799,0.0001247167,0.00008885838],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007677763,0.00002012656,0.0002133884,0.000005488466,0.000062875,0.00000766627,0.00006967122,0.00003473117,0.997103,0.0001011045,0.0003108975,0.001303269],"study_design_scores_gemma":[0.0009743032,0.0007457227,0.0004858341,0.00002935769,0.0001040902,0.0001824376,0.0002590631,0.000003725705,0.8789926,0.00003597901,0.1180652,0.0001216261],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9678549,0.001251712,0.02803206,0.0009060908,0.001024383,0.0001720769,0.0000182839,0.00000525841,0.0007351991],"genre_scores_gemma":[0.9976838,0.000374942,0.0001160984,0.0001810752,0.001175806,0.000002919575,0.00001842542,0.00001295433,0.0004340156],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1181104,"threshold_uncertainty_score":0.2487983,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007378119628239394,"score_gpt":0.2041508373466595,"score_spread":0.1967727177184201,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}