{"id":"W2483485727","doi":"10.1038/srep30443","title":"Human DNA-Damage-Inducible 2 Protein Is Structurally and Functionally Distinct from Its Yeast Ortholog","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Grantová Agentura České Republiky; Ministerstvo Školství, Mládeže a Tělovýchovy; Canada Research Chairs","keywords":"Ubiquitin; Biology; Cell biology; Yeast; Protein domain; Protease; Saccharomyces cerevisiae; Tandem affinity purification; Computational biology; Genetics; Biochemistry; Gene; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006382993,0.0005368328,0.0002311176,0.0002850547,0.0001972493,0.0003396677,0.0001720552,0.0002773709,0.002625701],"category_scores_gemma":[0.00009915604,0.0001355839,0.0002923663,0.0003053311,0.0001460055,0.0001518576,0.0002493578,0.0002581801,0.001831754],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002923077,"about_ca_system_score_gemma":0.0002182828,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000405843,"about_ca_topic_score_gemma":0.0005736573,"domain_scores_codex":[0.9999251,0.000005650872,0.000004660091,0.00003512813,0.000018247,0.00001123497],"domain_scores_gemma":[0.9999251,0.000007752837,0.00002742578,0.00001002443,0.000006283907,0.00002333326],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002327009,0.00003134018,0.001791434,0.0001321022,0.00001968346,0.000557168,0.00003405125,0.0001276445,0.9868565,0.0004930977,0.0003687303,0.009355521],"study_design_scores_gemma":[0.00007523406,0.0006385163,0.09767289,0.00004336431,0.00006197214,0.01680454,0.0001373697,0.001927659,0.7627868,0.0008045826,0.1190138,0.00003327265],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9734525,0.008206693,0.009321302,0.0002815065,0.0001087588,0.00005288487,0.003883635,0.0007250027,0.003967776],"genre_scores_gemma":[0.9619791,0.002241187,0.008475896,0.0001663111,0.00003968802,0.00006383707,0.01546985,0.00007546195,0.01148861],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002625701,"threshold_uncertainty_score":0.008783877,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01636998576918599,"score_gpt":0.2420388478285522,"score_spread":0.2256688620593662,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}