{"id":"W2484186823","doi":"10.1212/wnl.86.16_supplement.s38.002","title":"Hematopoietic Stem Cell Transplantation in Late-Onset Krabbe Disease Halts Demyelination and Axonal Loss: A 4-Year Longitudinal Case Study (S38.002)","year":2016,"lang":"en","type":"article","venue":"Neurology","topic":"Lysosomal Storage Disorders Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"North York General Hospital; University of British Columbia","funders":"","keywords":"Krabbe disease; Transplantation; Medicine; Hematopoietic stem cell transplantation; Stem cell; Disease; Neuroscience; Pathology; Biology; Internal medicine; Leukodystrophy; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005357552,0.0006013941,0.0006096851,0.000779225,0.001925294,0.0006766746,0.0006305558,0.001812771,0.001183779],"category_scores_gemma":[0.001071047,0.0004387207,0.000940881,0.0004298152,0.0006547428,0.0006545943,0.000799885,0.001547632,0.0005499329],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001239056,"about_ca_system_score_gemma":0.0006710117,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006203647,"about_ca_topic_score_gemma":0.007083961,"domain_scores_codex":[0.9996864,0.00004368222,0.00003472297,0.00007843424,0.0000502276,0.0001067479],"domain_scores_gemma":[0.9993114,0.00008401092,0.0002007096,0.00005649345,0.0001418891,0.0002054666],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.0009174941,0.003120048,0.4375453,0.0000996778,0.0001841086,0.5326666,0.004620753,0.0002115783,0.006489209,0.0002315124,0.00144907,0.01246463],"study_design_scores_gemma":[0.000125766,0.006873424,0.3908457,0.000100681,0.0001886798,0.59098,0.002124704,0.00055207,0.002530555,0.0002755628,0.005324384,0.00007846522],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983432,0.0005286122,0.0001617006,0.0002092101,0.0000175821,0.000028304,0.00007654641,0.000009789712,0.0006249661],"genre_scores_gemma":[0.9974793,0.0004128297,0.0002410703,0.0002168324,0.00004120798,0.00002057355,0.0002185962,0.00000825333,0.001361234],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006203647,"threshold_uncertainty_score":0.01233506,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02479708372387955,"score_gpt":0.2927017127426961,"score_spread":0.2679046290188165,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}