{"id":"W2484292592","doi":"10.1385/1592593941","title":"Protein Misfolding and Disease","year":2003,"lang":"en","type":"book","venue":"Humana Press eBooks","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":113,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Children's Hospital of Pittsburgh; Syddansk Universitet; University of Toronto; Universiteit Utrecht; Vedecká Grantová Agentúra MŠVVaŠ SR a SAV; University of Pittsburgh; Eberhard Karls Universität Tübingen; Department of Medicine, University of Toronto; Directorate for Biological Sciences; Aarhus Universitet; University of Chicago","keywords":"Protein folding; Folding (DSP implementation); Computational biology; Disease; Chemistry; Biology; Cell biology; Medicine; Engineering; Pathology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00005761897,0.0003668596,0.0002443454,0.00003956992,0.0001187851,0.00007739545,0.0001849909,0.0002480336,0.00002478001],"category_scores_gemma":[0.00005662757,0.0003617517,0.0001449315,0.000002792064,0.0001767687,0.000001663359,0.0001787797,0.0001609835,0.000004021838],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001705619,"about_ca_system_score_gemma":0.0002753733,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007404408,"about_ca_topic_score_gemma":0.000004426387,"domain_scores_codex":[0.9986229,0.00004939927,0.0002255206,0.0006319645,0.000181688,0.0002885572],"domain_scores_gemma":[0.998776,0.000005916517,0.0001342923,0.0005796019,0.00004978155,0.0004543913],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008610256,0.0002203131,0.00005524234,0.004430524,0.001075397,0.0007595604,0.0001612162,0.00002948849,0.01543438,0.173489,0.7702214,0.03326253],"study_design_scores_gemma":[0.0005763664,0.00007038873,0.00001233327,0.0002441314,0.000163625,0.000005646204,0.00000296546,0.000006978742,0.003941863,0.003770131,0.9906545,0.0005510422],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.004008257,0.04440387,0.00005699959,0.00001092737,0.0001267506,0.0008469929,0.0001707854,0.0000333214,0.9503421],"genre_scores_gemma":[0.008963392,0.0007985381,0.00009309353,0.0002301668,0.0003631625,0.0001754147,0.0002818109,0.00009256024,0.9890019],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.2204332,"threshold_uncertainty_score":0.9998835,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01961510046527718,"score_gpt":0.2385353616678881,"score_spread":0.2189202612026109,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}