{"id":"W2484616545","doi":"10.1182/blood-2016-02-699520","title":"Phase 2 study of panobinostat with or without rituximab in relapsed diffuse large B-cell lymphoma","year":2016,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":140,"is_retracted":false,"has_abstract":true,"ca_institutions":"Quebec - Clinical Research Organization in Cancer; Ozmosis Research (Canada); McGill University; Health Sciences Centre; University of British Columbia; Hôpital du Sacré-Cœur de Montréal; BC Cancer Agency; Princess Margaret Cancer Centre; Simon Fraser University; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Panobinostat; Rituximab; Diffuse large B-cell lymphoma; Oncology; Lymphoma; Internal medicine; Medicine; Refractory (planetary science); Cancer research; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009471935,0.0002088828,0.0005472838,0.0001234182,0.00003247145,0.000007236859,0.00007727852,0.00005861417,0.0000585525],"category_scores_gemma":[0.00003430373,0.00009879098,0.00005139203,0.0002020851,0.00003897462,0.00005074212,0.00003838479,0.00002992904,0.00003899746],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007642312,"about_ca_system_score_gemma":0.0001563855,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000157766,"about_ca_topic_score_gemma":0.0003482741,"domain_scores_codex":[0.9986759,0.0000562133,0.0003224617,0.0003387776,0.0003009681,0.0003056579],"domain_scores_gemma":[0.9991012,0.0001098958,0.0001196826,0.0004751411,0.00006027714,0.0001338045],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.002275688,0.4675395,0.5234408,0.00004061652,0.0001765578,0.001072358,0.0009588024,1.138662e-8,0.001614925,0.00001143462,0.00005662636,0.002812617],"study_design_scores_gemma":[0.8469838,0.01730109,0.08639071,0.0003250919,0.0007129666,0.0000887385,0.0009625736,0.000004088673,0.04667946,0.000004042612,0.000370565,0.0001768634],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979971,0.0001775263,0.000003989654,0.0001070579,0.00002905204,0.001045537,0.00003964433,0.00004188052,0.0005582179],"genre_scores_gemma":[0.9987968,0.00005736615,0.0001560366,0.00007352031,0.00002780596,0.0001551838,0.000006977221,0.00003241435,0.0006938882],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8447081,"threshold_uncertainty_score":0.4028579,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01396331256451666,"score_gpt":0.2718089834546433,"score_spread":0.2578456708901266,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}