{"id":"W2484696511","doi":"10.1371/journal.pone.0159070","title":"Cattle Immunized with a Recombinant Subunit Vaccine Formulation Exhibits a Trend towards Protection against Histophilus somni Bacterial Challenge","year":2016,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Microbial infections and disease research","field":"Immunology and Microbiology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Agriculture and Agri-Food Canada; Alberta Health; University of Saskatchewan","funders":"Alberta Livestock and Meat Agency","keywords":"Reverse vaccinology; Adjuvant; Titer; Group A; Recombinant DNA; Group B; Antibody titer; Antigen; Immunity; Biology; Microbiology; Antibody; Humoral immunity; Protein subunit; Virology; Immune system; Immunology; Medicine; Epitope; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003430441,0.0003721893,0.000407977,0.000299471,0.0001366376,0.0003293913,0.000183463,0.0004495361,0.0008114127],"category_scores_gemma":[0.0003741113,0.0001351986,0.0002173856,0.000131433,0.0002403196,0.0002152595,0.0001217174,0.0009013059,0.0002335668],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002052946,"about_ca_system_score_gemma":0.0001881213,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000805388,"about_ca_topic_score_gemma":0.000665338,"domain_scores_codex":[0.9996773,0.00005651188,0.00002995233,0.00007184929,0.00007138662,0.0000930766],"domain_scores_gemma":[0.9996762,0.00008511094,0.00007850424,0.00002514071,0.00005513984,0.00007982207],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006284486,0.0002130419,0.0008129677,0.0000705206,0.0000139431,0.00002526101,0.00004720431,0.00005132078,0.9966629,0.00002325846,0.00004365864,0.001407529],"study_design_scores_gemma":[0.000121444,0.02182524,0.04644443,0.00003385391,0.0001395633,0.00044828,0.0002180452,0.001135392,0.9276288,0.00007862433,0.001909728,0.00001665473],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985676,0.0002912068,0.0005259394,0.00005582976,0.00002190488,0.00001902334,0.00008540222,0.00002414996,0.0004088564],"genre_scores_gemma":[0.9974648,0.0002750545,0.0007902576,0.00007245997,0.00001327169,0.00002200336,0.0003407802,0.00001049605,0.001010775],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008114127,"threshold_uncertainty_score":0.002714396,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04887306651869113,"score_gpt":0.2335871367225796,"score_spread":0.1847140702038885,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}