{"id":"W2485024460","doi":"10.1158/1538-7445.am2016-4134","title":"Abstract 4134: Immune infiltration and PD-L1 expression in the tumor microenvironment are prognostic in osteosarcoma","year":2016,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Immunohistochemistry; Immune system; Tumor microenvironment; Medicine; Osteosarcoma; PD-L1; Immune checkpoint; Immunotherapy; Cancer research; CD68; Tumor-infiltrating lymphocytes; Antigen; Infiltration (HVAC); Antibody; Oncology; Internal medicine; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002606249,0.000139569,0.0002108887,0.0003149288,0.0001622372,0.0003303098,0.00009757546,0.0002182246,0.003092666],"category_scores_gemma":[0.0004022382,0.000115651,0.0001060531,0.0002563357,0.0001825115,0.00020288,0.0001678585,0.0002713975,0.000467141],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001440512,"about_ca_system_score_gemma":0.0001420353,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001879861,"about_ca_topic_score_gemma":0.0002879652,"domain_scores_codex":[0.9999125,0.00001440884,0.00001195806,0.00002251124,0.00002446173,0.00001423072],"domain_scores_gemma":[0.9997696,0.00005058295,0.00009041231,0.00001338061,0.00003449145,0.0000415206],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.005732893,0.0002956896,0.7457175,0.0002411741,0.00005261438,0.0006174996,0.0001479382,0.0003257231,0.2164328,0.00009873781,0.0008909688,0.02944637],"study_design_scores_gemma":[0.0001265784,0.001510327,0.960639,0.00003363073,0.000133883,0.003129041,0.0002327913,0.001658458,0.02941042,0.0002333953,0.002882619,0.000009800785],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986134,0.0006419101,0.0002261632,0.00004437887,0.000006968262,0.000008995337,0.0001146957,0.00001040061,0.0003330546],"genre_scores_gemma":[0.9990282,0.0001762279,0.0001593318,0.0000166069,0.00001130507,0.000008781939,0.0001749751,0.000002308926,0.0004223079],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003092666,"threshold_uncertainty_score":0.01034606,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05030626678690519,"score_gpt":0.3558987547307891,"score_spread":0.3055924879438839,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}