{"id":"W2485350468","doi":"10.1007/978-1-61779-915-0_8","title":"Immobilization of Fluorescent Aptamer Biosensors on Magnetic Microparticles and Its Potential Application for Ocean Sensing","year":2012,"lang":"en","type":"book-chapter","venue":"Springer protocols handbooks/Springer protocols","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"","keywords":"Aptamer; Biosensor; Analyte; Fluorescence; Nucleic acid; Ionic strength; Nanotechnology; Chemistry; Salt (chemistry); Combinatorial chemistry; Chromatography; Biochemistry; Materials science; Biology; Molecular biology; Aqueous solution; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000535781,0.0007717784,0.0007642793,0.0002568285,0.0001811562,0.00007958554,0.0002901814,0.0007216499,0.000007380717],"category_scores_gemma":[0.00006708592,0.0007294324,0.0003776385,0.00006051939,0.0002753253,0.00001736486,0.0002734642,0.0002853788,0.000008700161],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007067008,"about_ca_system_score_gemma":0.0001002605,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003588689,"about_ca_topic_score_gemma":0.000005546508,"domain_scores_codex":[0.9967878,0.00007120467,0.00098214,0.001159422,0.0004109528,0.0005884658],"domain_scores_gemma":[0.9973937,0.00002747639,0.0009143099,0.0009467278,0.0005131636,0.000204646],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009375159,0.0001471282,0.00007267397,0.0009028605,0.000131716,0.000002156397,0.00002979934,0.00001340937,0.9591577,0.001115914,0.00009827207,0.03739088],"study_design_scores_gemma":[0.001126305,0.0012079,0.00005523348,0.00141732,0.0001495366,0.00001441337,0.000005080052,0.0002635824,0.909675,0.0005170633,0.08480534,0.0007632369],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.01360017,0.0008156687,0.01231479,0.00009893386,0.00009544924,0.9708702,0.0001966266,0.0002974891,0.001710646],"genre_scores_gemma":[0.3492416,0.0003492049,0.0366648,0.0003699941,0.002469441,0.5878728,0.000436597,0.0009799887,0.02161564],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.3829975,"threshold_uncertainty_score":0.9995157,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02006526198531061,"score_gpt":0.2913297649098585,"score_spread":0.2712645029245479,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}