{"id":"W2486104543","doi":"10.1002/ejoc.201600578","title":"<i>N</i>‐<i>tert</i>‐Butylsulfinyl‐3,3,3‐trifluoroacetaldimine: Versatile Reagent for Asymmetric Synthesis of Trifluoromethyl‐Containing Amines and Amino Acids of Pharmaceutical Importance","year":2016,"lang":"en","type":"article","venue":"European Journal of Organic Chemistry","topic":"Fluorine in Organic Chemistry","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Natural Science Foundation of China; Ikerbasque, Basque Foundation for Science; Hillman Foundation; Canadian Bee Research Fund","keywords":"Trifluoromethyl; Reagent; Chemistry; Enantioselective synthesis; Novelty; Combinatorial chemistry; Aldimine; Organic chemistry; Amino acid; Catalysis; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002461477,0.0004227798,0.0002077171,0.0002543724,0.0001308536,0.0001343298,0.00026726,0.0004301209,0.001159103],"category_scores_gemma":[0.0001294384,0.0001234805,0.000195396,0.0001698985,0.0002044876,0.0004011882,0.0001622398,0.000407985,0.0007938198],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001886992,"about_ca_system_score_gemma":0.0001935266,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000227232,"about_ca_topic_score_gemma":0.0003226139,"domain_scores_codex":[0.9999104,0.00001920095,0.000006358443,0.00001430797,0.00002466572,0.00002513305],"domain_scores_gemma":[0.9999589,0.000008208059,0.00001744645,0.000002616098,0.000005527868,0.000007360126],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009725941,0.00002441083,0.00009101542,0.0005683391,0.00001071911,0.0003179153,0.0000474175,0.0002363452,0.9770744,0.001796611,0.000837849,0.01889767],"study_design_scores_gemma":[0.00002656202,0.0005437658,0.0008685068,0.00003740112,0.00001865548,0.002690478,0.00003202992,0.0006552674,0.9589958,0.0004378282,0.03566813,0.00002552019],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6233311,0.1484661,0.1697006,0.002405395,0.001021908,0.0003380591,0.0008313276,0.001001342,0.05290405],"genre_scores_gemma":[0.9042594,0.04396219,0.03890701,0.000524352,0.0002357546,0.0001554156,0.0005553398,0.00007202896,0.01132848],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001159103,"threshold_uncertainty_score":0.00387758,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05619316260627236,"score_gpt":0.3435039426562206,"score_spread":0.2873107800499483,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}